Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hairgrowth without disrupting the skin microbiome. sCD83 promotes hairgrowth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.
KPV, a peptide patented by L'Oreal, may promote hairgrowth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hairgrowth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hairgrowth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.