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This case report suggests that methotrexate therapy for psoriasis may lead to hair regrowth in androgenetic alopecia, potentially due to its effects on testosterone metabolism.

This study found that men with early-onset androgenetic alopecia who also met criteria for the male PCOS-equivalent may have impaired gonadal steroidogenesis, suggesting increased risk of future gonadal dysfunction.

This review discusses the pathways of androgen biosynthesis and reports no new findings, highlighting the need to understand the interplay between the classic and backdoor pathways.

In this study, PFOS exposure altered steroid hormone levels and enzyme activities related to steroidogenesis in juvenile Silurana tropicalis, with effects differing between male and female frogs.

This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.