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GlossaryGingival Hyperplasia (Gingival Overgrowth)

excessive growth of gum tissue around the teeth

Gingival Hyperplasia, also known as Gingival Overgrowth, is a condition characterized by an excessive growth of gum tissue around the teeth. This can be caused by factors such as certain medications (e.g., anticonvulsants, immunosuppressants, and calcium channel blockers), hormonal changes, or chronic inflammation due to plaque buildup. The overgrown gums can make oral hygiene difficult, potentially leading to periodontal disease if not managed properly.

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research Phenytoin-Mediated Androgen Metabolism in Gingival Fibroblasts

8 citations , October 2002 in “Journal Of Clinical Periodontology”

Levamisole and finasteride can reduce DHT production, potentially preventing phenytoin-induced gum overgrowth.

research Cosmetic Adverse Effects of Antiseizure Medications: A Systematic Review

7 citations , May 2021 in “Seizure”

Some antiseizure medications can cause cosmetic problems like hair loss, excessive hair growth, acne, and gum overgrowth.

research Cutaneous Toxicities From Transplantation-Related Medications

14 citations , April 2017 in “American Journal of Transplantation”

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

research Side Effects of Transplant Immunosuppressive Therapy in Post Renal Transplant Recipients, Mazandaran, Northern Iran

3 citations , April 2017 in “Zahedan Journal of Research in Medical Sciences”

Almost all kidney transplant patients had complications from immunosuppressive therapy, with excessive hair growth being the most common.

research PC040: Amalgam Tattoo of the Oral Mucosa

June 2018 in “Journal of Clinical Periodontology”

Finasteride may cause gum problems, but stopping the drug can improve these issues.

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