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Expression Patterns of Glial Cell Line-Derived Neurotrophic Factor, Neurturin, Their Cognate Receptors GFRα-1, GFRα-2, and Common Signal Transduction Element c-Ret in Human Skin Hair Follicles

research Expression Patterns of Glial Cell Line-Derived Neurotrophic Factor, Neurturin, Their Cognate Receptors GFRα-1, GFRα-2, and Common Signal Transduction Element c-Ret in Human Skin Hair Follicles

18 citations, January 2008 in “Journal of The American Academy of Dermatology”

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

research Reawakening GDNF's Regenerative Past in Mice and Humans

1 citations, April 2022 in “Regenerative Therapy”

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

research SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells

77 citations, February 2017 in “Stem Cell Reports”

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

research GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells

7 citations, June 2020 in “npj regenerative medicine”

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

research Age-Associated Decrease in GDNF and Its Cognate Receptor GFRα-1 Protein Expression in Human Skin

2 citations, June 2016 in “International journal of experimental pathology”

Human skin has less GDNF and its receptor with age.

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community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 2 months ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community Got my bloodwork done today, I have been on fin for 7+ months. 21m

in Update 32 upvotes 1 year ago

A user on finasteride for 7+ months shared bloodwork results, questioning if high DHT levels and testosterone could affect cholesterol. Replies suggest consulting a doctor and question the high testosterone levels.

community 4C Afro results (your hair texture can change while on treatment) 5 months- Minoxidil 1ml 2x/day, dutasteride 0.5mg 3x/week, no micro needling. No regrets

in Progress Pictures 302 upvotes 1 year ago

The post is about a user's hair loss progress using Minoxidil and dutasteride treatments. The conclusion is that the user has seen positive results after 5 months of treatment and has no regrets.

community Fin and Min progress about 4 months progress.

in Progress Pictures 175 upvotes 11 months ago

The user showed a significant improvement in hair density after four months using finasteride and minoxidil. They also used a micro needle pen, hair care like coconut oil, and improved their diet.

community 5 Months Hair Transplant Progress / 3500 Grafts

in Transplants 1663 upvotes 1 year ago

A user shared their positive experience with a hair transplant of 3500 grafts, showing significant improvement in appearance after 5 months. They underwent the procedure at Heva Clinic in Istanbul for $2,300 USD, which included aftercare, and attributed their hair loss to both genetics and traction alopecia from tight hairstyles.