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      Pharmacovigilance Profiles of Three Generations of Mineralocorticoid Receptor Antagonists and Network Toxicology Analysis

      research Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis

      June 2026 in “Frontiers in Medicine”
      This study conducted a large-scale comparison using FAERS data to assess the post-marketing safety profiles of spironolactone, eplerenone, and finerenone, finding unique adverse event patterns for each drug and highlighting the need for personalized safety monitoring and further investigation in other pharmacovigilance databases.
      Drug Repurposing Patent Applications July–September 2025

      research Drug Repurposing Patent Applications July–September 2025

      January 2025 in “Drug repurposing”
      This study reviewed 16 notable drug repurposing patent applications from 2025, highlighting potential new uses such as guanfacine for autonomic dysfunction and disulfiram for subarachnoid hemorrhage survival, though many disclosures lack peer-reviewed studies and no patents are granted.