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Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

20 citations , June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery”

This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.

research Tatalaksana Alopesia Androgenetik

August 2018

This article discusses the impact of androgenetic alopecia, highlighting its genetic and hormonal causes and its significant psychological and quality of life effects, but reports no new clinical findings.

research Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: What is in common?

23 citations , December 2004 in “Differentiation”

This article reviews the interaction between sex hormone pathways and morphogenesis-related signaling in epithelial organ development, using a chicken model to propose testable hypotheses, but reports no new clinical results.

research Hormones and the pilosebaceous unit

97 citations , March 2009 in “Dermato-endocrinology”

This review explores the role of hormones in pilosebaceous units and associated skin disorders, focusing on androgen action, without presenting new clinical findings.

research Redefining hormone resistance in prostate cancer

38 citations , December 2009 in “Therapeutic Advances in Medical Oncology”

This discussion proposes a model to incorporate patients with hormone-resistant prostate cancer into the existing framework by redefining hormone resistance and exploring new therapeutic approaches.

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Community Join

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community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?

5 upvotes 2 years ago

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly

6 upvotes 5 years ago

User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.

community Does anyone have any experience with Estradiol, Cyproterone Acetate, Spironolactone, Bicalutamide ?

4 upvotes 6 years ago

Some users have experienced good hair regrowth with estradiol, cyproterone acetate, spironolactone, and bicalutamide, but these treatments may cause feminization and other side effects. It's advised to consult a doctor before using these treatments, as they can lower testosterone and have significant risks.

community Need supplemental products in addition to oral minoxidil and oral dutasteride

1 upvotes 1 year ago

The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

community Can you take something like Spiro or even Estradiol if already on low dose TRT to regrow hair?

3 upvotes 1 year ago

The conversation discusses using treatments like dutasteride, minoxidil, spironolactone, and estradiol for hair regrowth while maintaining muscle mass. Concerns include potential side effects like gynecomastia and muscle loss, with suggestions to balance hormone levels carefully.

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Learn

5 / 801 results

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

learn dehydroepiandrosterone

learn GT20029

research compound made to degrade androgen receptors in scalp

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