research Exogenous and endogenous lipids of human hair
In this study, extracting internal lipids from Caucasian hair fibers led to decreased water permeability, influenced by the fluidity of lipids.
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5 / 1000+ results research Characterization of the lipid composition at the proximal root regions of human hair
This study observed that in Japanese females, hair lipid composition showed significant correlations, suggesting CH and CERs may act as a barrier against sebum-derived lipids.
research Characterization of hair lipid images by argon sputter etching-scanning electron microscopy
This study found that in Japanese, German, and American females, changes in hair lipid patterns with age may reflect alterations in sebum excretion and affect hair texture.
research Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T
This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.
research Endogenous retinoids in the hair follicle and sebaceous gland
This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.
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5 / 1000+ resultscommunity Having androgen receptor density and sensitivity at wrong f*ing place
The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.
community 18 months Dut - Shed after shed without any gains
Dutasteride caused persistent hair shedding and no improvement for 18 months, leading to a switch back to finasteride. The user also uses oral minoxidil and plans to focus on better scalp health.
community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
community Oral minoxidl - Is this a medication that's generally safe to take for life? Like what I understand oral fin is? Also do studies show that in general or in a significant amount of more cases that results with oral minox + oral fin > oral fin in terms of long-term use(talkin 20+ years).
Oral minoxidil combined with finasteride can improve hair density, but long-term safety is uncertain due to potential side effects like heart and kidney issues. Users report mixed experiences, with some experiencing side effects and others finding it effective for hair maintenance.
community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
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