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    Did you mean Estrogen Therapy?
    GlossaryEstrogen Therapy

    administration of estrogen hormones to alleviate menopause symptoms

    Estrogen Therapy, also known as Hormone Replacement Therapy (HRT) or Estrogen Replacement Therapy (ERT), involves the administration of estrogen hormones to alleviate symptoms associated with menopause, such as hot flashes, vaginal dryness, and osteoporosis. It can also be used in cases of estrogen deficiency due to other medical conditions. This therapy helps to restore hormone levels, thereby improving quality of life and reducing the risk of certain long-term health issues.

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      an estrogen promoting hair regrowth more commonly used in women

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      a synthetic estrogen used topically as an anti-androgen

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      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

    Research

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      Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients

      research Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients

      October 2024 in “Journal of the Endocrine Society”
      This study retrospectively reviewed estrogen monotherapy for testosterone suppression in gender diverse individuals assigned male at birth, specifically focusing on transfeminine patients. Out of 10 patients, 7 transfeminine individuals achieved testosterone suppression with serum estradiol levels over 100 pg/mL, using either injectable or transdermal estrogen formulations. Injectable estradiol valerate (4-6 mg weekly) and transdermal patches (0.2 mg twice weekly to 0.3 mg three times weekly) were effective. The study suggests estrogen monotherapy could be a viable alternative to anti-androgens, though the small sample size is a limitation. Further research is needed to confirm these findings and potentially simplify treatment protocols.
      Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients

      research Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients

      October 2024 in “Journal of the Endocrine Society”
      This study retrospectively reviewed estrogen monotherapy for testosterone suppression in gender diverse individuals assigned male at birth, specifically focusing on transfeminine patients. Out of 10 patients aged 19-81, 7 transfeminine patients achieved testosterone suppression with serum estradiol levels over 100 pg/mL, using either injectable or transdermal estrogen formulations. Injectable formulations were more common among those who achieved suppression. The study suggests that estrogen monotherapy could be effective without anti-androgens, though the small sample size is a limitation. Further research is needed to explore its potential for simplifying treatment protocols.
      New Approaches to the Treatment of Osteoporosis

      research New Approaches to the Treatment of Osteoporosis

      28 citations, August 2000 in “Current Opinion in Chemical Biology”
      Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

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