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      research Einfluss des Lipidmusters und der Morphologie der Epidermis auf transdermale Permeationsraten im In-vitro-Versuch

      1 citations , January 2007
      This study investigated the influence of epidermal morphology and lipid composition on transdermal drug permeation using in-vitro experiments with skin from cattle, pigs, dogs, and rats. It was found that both the thickness of the stratum corneum and total epidermal lipid content significantly affected the permeation rates of nonsteroidal anti-inflammatory drugs, with a general permeation ranking of pig < dog < cattle < rat. The study concluded that porcine skin is a suitable substitute for human skin in diffusion experiments due to its similar morphological and lipid characteristics, although dog, cattle, and rat skin can also be useful depending on the study's purpose. Contrary to previous reports, no direct influence of specific epidermal lipid fractions on drug permeation was detected.
      Integral Hair Lipid in Human Hair Follicle

      research Integral Hair Lipid in Human Hair Follicle

      36 citations , August 2011 in “Journal of dermatological science”
      Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
      Stratum Corneum Dysfunction in Dandruff

      research Stratum Corneum Dysfunction in Dandruff

      93 citations , April 2012 in “International Journal of Cosmetic Science”
      Improving skin barrier and using antifungal treatments can help manage dandruff.

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