research Cicatrising Alopecias.
This study suggests that pseudopelade may be an autonomous disease based on its distinctive clinical and histopathological features not present in other scarring alopecias.
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5 / 1000+ resultsresearch 509 Using the human iPSCs-derived sensory neurons re-innervated skin ex vivo model to investigate mast cell-nerve fiber cross-talk in solar elastosis
In this study, UVB irradiation increased mast cell degranulation only when skin was innervated, suggesting that the interaction between mast cells and nerve fibres may exacerbate solar elastosis by promoting dysfunctional dermal elastic fiber accumulation, but further research is needed for confirmation.
research 1447 Anti-senescence effect of extracellular vesicle from hyaluronic acid primed induced mesenchymal stem cells on aged human dermal fibroblast
HA-iMSC-EVs can improve skin aging by boosting cell growth and restoring collagen and elastin.
research Inhalation therapy for repairing damaged elastin fibers and decelerating elastinolysis in chronic obstructive pulmonary disease
This article reviews the potential of inhalation therapy to restore pulmonary elastin fibers in COPD patients and highlights the need for studies to test its feasibility; it reports no new research findings.
research Chronic Treatment with Minoxidil Induces Elastic Fiber Neosynthesis and Functional Improvement in the Aorta of Aged Mice
In this study, minoxidil treatment in aged mice increased elastin expression and improved aortic structure and function, suggesting its potential for arterial remodeling in aging.
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4 / 1000+ resultscommunity Is 2-deoxy-D-ribose (2dDR) good for human hair?
Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).
community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?
Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.
community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
community Anybody else notice improved skin/collagen on Dutasteride
User switched from finasteride to combination dutasteride and finasteride for hair density improvement. They noticed less hair shedding and more youthful skin, with a reply suggesting less DHT could increase elastin in skin.
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