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This study found that in mice with alopecia areata, CD8+ T cells showed clonal expansion and specific regulatory networks, which might help identify new therapeutic targets for patients not responding to JAK inhibitors.

In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.

This study found that IL-7 is crucial for the survival of memory regulatory T cells in the skin of mice, whereas IL-2 is essential for their initial generation but not for their maintenance.

This study found that in alopecia areata, treatment with the oral JAK-inhibitor tofacitinib decreased clonally expanded CD8⁺ T cells in the scalp, but many expanded clones did not completely disappear, potentially leading to relapse after stopping treatment.

D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.