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GlossaryDoxorubicin (Dox)

chemotherapy drug that interferes with cancer cell DNA

Doxorubicin, also known as Adriamycin, is a chemotherapy drug used to treat various types of cancer, including breast cancer, bladder cancer, and lymphoma. It works by interfering with the DNA inside cancer cells, preventing them from growing and dividing. However, it can also cause side effects such as hair loss (alopecia) and damage to the heart, so its use is carefully monitored by healthcare professionals.

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research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

1707 citations, December 2003 in “The New England Journal of Medicine”

Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.

Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

research Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

1461 citations, March 2004 in “Annals of oncology”

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

522 citations, January 2001 in “Cancer investigation”

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer

108 citations, December 2003 in “Clinical breast cancer”

PLD is an effective and safer alternative for treating breast cancer.

research Copper-Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity

102 citations, October 2010 in “Molecular Pharmaceutics”

Copper-doxorubicin nanoparticles effectively treat tumors with less toxicity.

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community Inflammation (and health care system) frustration

in Female 3 upvotes 3 months ago

A woman is frustrated with her hair loss and the slow, ineffective healthcare system in Canada. She has tried treatments like minoxidil, doxycycline, and kenalog injections, but continues to experience painful inflammation and hair loss.

community Starting Treatment for CCCA (scarring alopecia)

in Treatment 6 upvotes 1 year ago

A male in his early 20s with CCCA (scarring alopecia) started treatment with Finasteride, Fluocinolone, and Doxycycline. Steroid injections were suggested but not yet done.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 40 upvotes 2 months ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community The Truth About DUPA and Retrograde: My Research Summary

in Research/Science 19 upvotes 7 months ago

The conversation discusses the importance of scalp biopsies for diagnosing hair loss conditions like DUPA and Retrograde, which may not be just AGA. It emphasizes that treatments like finasteride and dutasteride may not work if the condition is autoimmune.

community TE turned into Scarring hairloss

in Update 12 upvotes 1 year ago

The user experienced hair loss due to a crash diet and later developed scarring hair loss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.

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