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GlossaryDoxorubicin (Dox)

chemotherapy drug that interferes with cancer cell DNA

Doxorubicin, also known as Adriamycin, is a chemotherapy drug used to treat various types of cancer, including breast cancer, bladder cancer, and lymphoma. It works by interfering with the DNA inside cancer cells, preventing them from growing and dividing. However, it can also cause side effects such as hair loss (alopecia) and damage to the heart, so its use is carefully monitored by healthcare professionals.

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research Cepharanthine Inhibits Doxorubicin-Induced Cellular Senescence by Activating Autophagy via the MTOR Signaling Pathway

January 2023 in “Discovery medicine”

Cepharanthine helps reduce cell aging caused by the cancer drug Doxorubicin by boosting cell cleanup processes.

A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4

research A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4

17 citations , January 2019 in “Journal of cancer”

The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.

Overexpression of Cyclooxygenase-2 in the Skin of Adult Transgenic Mice Leads to Sebaceous Gland Hyperplasia and Thinning of Hair Shafts

research Overexpression of Cyclooxygenase-2 in the Skin of Adult Transgenic Mice Leads to Sebaceous Gland Hyperplasia and Thinning of Hair Shafts

April 2019 in “Journal of Investigative Dermatology”

Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.

Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models

research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models

9 citations , April 2021 in “Evidence-based complementary and alternative medicine”

Guilu Erxian Glue may help reduce chemotherapy side effects like weight loss and heart stress.

research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation

2 citations , September 2017 in “Biotechniques/BioTechniques”

Researchers created a mouse cell line to study hair growth and test hair growth drugs.

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community Medications that cause extra hair growth

in Research/Science 123 upvotes 2 years ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 3 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community So depressed and upset with how much progress I’ve lost

in Chat 51 upvotes 2 years ago

A 20-year-old started taking finasteride for hair loss at 18, saw improvement, but developed erectile dysfunction (ED) after taking accutane. Despite stopping both medications, ED persisted, and hair loss worsened. Advice given includes considering tadalafil for ED, resuming finasteride, using minoxidil, and addressing psychological factors through positive thinking and lifestyle changes.

community Starting Treatment for CCCA (scarring alopecia)

in Treatment 6 upvotes 2 years ago

A male in his early 20s with CCCA (scarring alopecia) started treatment with Finasteride, Fluocinolone, and Doxycycline. Steroid injections were suggested but not yet done.

community Huberman tweet about finasteride

in Finasteride/Dutasteride 278 upvotes 2 years ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

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