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Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

research Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

May 2023 in “Cytotherapy”

Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.

research Abnormal Neuronal Differentiation and Mitochondrial Dysfunction in Hair Follicle-Derived Induced Pluripotent Stem Cells of Schizophrenia Patients

198 citations , June 2013 in “Molecular psychiatry”

Schizophrenia patients' stem cells show abnormal neuron development and mitochondrial issues.

research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease

September 2024 in “Frontiers in Neuroendocrinology”

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

research The 5α-Reductase Inhibitor Dutasteride but Not Finasteride Protects Dopamine Neurons in the MPTP Mouse Model of Parkinson’s Disease

27 citations , May 2015 in “Neuropharmacology”

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats

13 citations , December 2017 in “CNS Neuroscience & Therapeutics”

Finasteride affects young male rats' brain function and behavior negatively.

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Community Join

5 / 8 results

community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 4 months ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community I've been afflicted by post finasteride syndrome, what now?

in Finasteride 43 upvotes 6 years ago

A user experienced severe side effects from finasteride, including mental health issues and physical symptoms, and sought advice on managing post-finasteride syndrome. Suggestions included checking vitamin levels, considering dopamine agonists, and avoiding further psychiatric medications.

community HMI-115 when will it be available

in Research/Science 16 upvotes 2 years ago

The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

community Any finasteride users have a history of depression?

in Finasteride/Dutasteride 26 upvotes 1 year ago

The conversation discusses finasteride for hair loss, especially among those with a history of depression. Users shared mixed experiences, with some reporting no issues and others experiencing worsened depression.

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