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FUE transplants for advanced baldness are challenging, with success depending on donor hair availability. Some suggest trying medications like Minoxidil and Finasteride first, while others recommend consulting with specialists like Zarev or Pitella.

A youthful hairline is preferred over an age-appropriate one for hair transplants, but factors like donor hair availability and response to treatments like finasteride must be considered. Surgeons should aim for the most aesthetically pleasing hairline while managing long-term hair loss.

Hair cloning technology is advancing, with clinical trials for improved methods expected by 2028 and 2029, potentially offering a solution for hair loss if donor follicles remain. Organtech's expansion into other biotech areas may secure funding, but the effectiveness of cloning depends on the availability of androgen-resistant donor follicles.

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

The user replaced finasteride with saw palmetto due to availability issues and experienced side effects, leading to adjustments in their regimen. They use saw palmetto, minoxidil, Nizoral, and a dermaroller, reporting reduced side effects and some benefits, with hair fall ranging from 5 to 20 hairs daily.