research Power Boosting the Grafts in Hair Transplantation Surgery*
This study found that preserving hair micrografts in an enriched storage medium for five hours significantly increased their survival rate compared to those stored in saline.
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5 / 92 results research Iron Chelators in the Management of Autoimmune-Induced Alopecia: A Focus on Hypoxia-Inducible Factor 1 Modulation and Hair Restoration
This study highlighted the potential of iron chelators, deferoxamine and deferiprone, to improve hair density, thickness, and elasticity and reduce hair loss by up to 66.8% over six months in individuals with autoimmune alopecia, suggesting they may offer a promising therapeutic option.
research 1328 HIF1A stabilisation in the human hair follicle promotes glycolysis
In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.
research 280 Investigation into the role of HIF-1A stabilisation in hair follicle metabolism
This study found that stabilizing HIF1A in hair follicle cells promoted a shift to glycolysis, potentially reducing oxidative stress and promoting hair growth, particularly in balding dermal papilla cells.
research TRAIL sensitization of PC3 prostate cancer cells by doxorubicin can be blocked by the anti-oxidant N-acetyl-cysteine or by the iron chelator deferoxamine
This study found that doxorubicin-induced oxidative stress downregulates FLIPs and phosphorylates EF2, sensitizing prostate cancer cells to TRAIL; antioxidants may reduce doxorubicin's effectiveness, warranting further investigation.
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