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GlossaryKeratin 2

protein providing structural strength to skin, hair, and nails

Keratin 2 (KRT2) is a type of protein found in the outer layer of the skin, hair, and nails. It plays a crucial role in providing structural strength and resilience to these tissues, helping to protect them from damage and wear. Mutations in the KRT2 gene can lead to skin disorders such as ichthyosis bullosa of Siemens, which is characterized by blistering and scaling of the skin.

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The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

research The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

70 citations, December 2004 in “Differentiation”

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

research A Case of Trichogerminoma: A Rare Cutaneous Follicular Neoplasm

December 2021 in “Pathologica”

Trichogerminoma is a rare, benign skin tumor from hair cells, with a small risk of becoming cancerous.

research The Clinicopathological Spectrum of Trichoepitheliomas: A Retrospective Descriptive Study

6 citations, July 2015 in “International Journal of Dermatology”

Trichoepitheliomas can be hard to distinguish from other skin conditions and often start in teenage years.

research The Developmental and Molecular Requirements for Ensuring That Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation

4 citations, January 2021 in “Cell transplantation”

Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.

research CD34 Glycoprotein Identifies Putative Stem Cells Located in the Isthmic Region of Canine Hair Follicles

21 citations, July 2006 in “Veterinary dermatology”

CD34 marks potential stem cells in dog hair follicles.

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