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    GlossaryAplasia Cutis Congenita (congenital skin defect)

    congenital absence of skin, often on the scalp

    Aplasia Cutis Congenita (ACC) is a rare congenital condition characterized by the absence of skin at birth, typically manifesting as a localized area without skin, most commonly on the scalp. The affected area can vary in size and may sometimes involve underlying structures such as bone or dura. While the exact cause is often unknown, ACC can be associated with genetic factors, teratogens, or other syndromes.

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Hair loss research is a money grab

      in Chat  217 upvotes 1 month ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community I was on 2.5 mg oral minoxidil

      in Progress Pictures  468 upvotes 1 year ago
      User took 2.5 mg oral minoxidil, saw hair growth but stopped due to excessive body hair. Recently started finasteride and plans to update progress.
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