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GlossaryBirth Defects (Congenital Disorders)

structural or functional abnormalities present at birth

Birth defects, also known as congenital disorders or congenital anomalies, are structural or functional abnormalities that occur during intrauterine development. These defects can affect various parts of the body, including the heart, brain, or limbs, and can result from genetic factors, environmental exposures, or a combination of both. They can range from minor issues that may not require treatment to severe conditions that can significantly impact a person's quality of life or even be life-threatening.

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research A Polarizing Light Microscopy Can Be an Easy and Reliable Diagnostic Tool of Congenital Keratinizing Disorders Including Netherton Syndrome

September 2016 in “Journal of Dermatological Science”

Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.

research Contribution of Environmental Constituents in the Genomic Disruption of Cytokeratins

1 citations , July 2021 in “IntechOpen eBooks”

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

research Keratin Disorders: From Gene to Therapy

109 citations , September 2011 in “Human molecular genetics online/Human molecular genetics”

New treatments targeting specific genes show promise for treating keratin disorders.

research Madarosis: A Marker of Many Maladies

36 citations , January 2012 in “International Journal of Trichology”

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

research Off-Label Uses of Retinoids in Dermatology

6 citations , September 2012 in “Our Dermatology Online”

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

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community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 10 upvotes 2 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Is this Better Than Topical Minoxidil? Topical Diazoxide

in Research/Science 6 upvotes 7 months ago

Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

community 31M. Just diagnosed with androgenic alopecia. Fears of min.

in Finasteride/Dutasteride 12 upvotes 2 months ago

A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.

community Questions on Minoxidil and Finasteride Efficacy After 10 Years of Hair Loss

in General 265 upvotes 4 months ago

Topical minoxidil with finasteride can help focus treatment on the scalp, with shedding being normal initially. Foam minoxidil is easier to apply, PRP's effectiveness varies, and anti-dandruff shampoos like ketoconazole are beneficial for scalp health.

community Boys,Thank you all. almost 90days into treatment. dut/minox/ketoconazole shampoo

in Progress Pictures 79 upvotes 1 year ago

The user is using oral dutasteride, topical minoxidil (Regaine foam 5%), and ketoconazole shampoo for hair loss, reporting good results with no significant side effects. The user is 26 years old and applies minoxidil once or twice daily.

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