Search

for
Search:

Glossary21-hydroxylase deficiency (congenital adrenal hyperplasia due to 21-hydroxylase deficiency)

genetic disorder impairing adrenal hormone production, causing excess androgens

21-hydroxylase deficiency, also known as 21-OHD, is a genetic disorder that affects the adrenal glands' ability to produce certain hormones, specifically cortisol and aldosterone. This enzyme deficiency leads to an overproduction of androgens, which can cause symptoms such as ambiguous genitalia in newborns, early puberty, and severe salt-wasting crises.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 1000+ results

research Clinical, Biochemical, and Molecular Characteristics of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

December 2024 in “Journal of Clinical Research in Pediatric Endocrinology”

21-hydroxylase deficiency causes hormone imbalances leading to various symptoms, and diagnosis involves clinical and genetic tests.

The Diagnosis of Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Based on Serum Basal or Post-ACTH Stimulation 17-Hydroxyprogesterone Can Lead to False-Positive Diagnosis

research The Diagnosis of Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Based on Serum Basal or Post-ACTH Stimulation 17-Hydroxyprogesterone Can Lead to False-Positive Diagnosis

25 citations , September 2015 in “Clinical Endocrinology”

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women

research Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women

117 citations , May 2017 in “Human Reproduction Update”

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

research Steroid 17-Hydroxyprogesterone in Hair as a Potential Long-Term Biomarker of Androgen Control in Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

10 citations , November 2019 in “Neuroendocrinology”

Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.

research Reproductive Outcomes of Female Patients with Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency

14 citations , January 2013 in “Indian Journal of Endocrinology and Metabolism”

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

View more "congenital adrenal hyperplasia due to 21-hydroxylase deficiency" in research →

Community Join

5 / 23 results

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 1 year ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community How a follicle next to it is so genetically different that it never miniaturized??

in Chat 219 upvotes 2 months ago

Genetic differences in hair follicles affect hair loss patterns. Treatments discussed include finasteride, dutasteride, minoxidil, and RU58841.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 156 upvotes 4 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 10 upvotes 2 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Is this Better Than Topical Minoxidil? Topical Diazoxide

in Research/Science 6 upvotes 7 months ago

Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

View more "congenital adrenal hyperplasia due to 21-hydroxylase deficiency" in community →