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GlossaryTUNEL assay (TUNEL)

detects DNA fragmentation in cells undergoing apoptosis

The TUNEL assay, or Terminal deoxynucleotidyl transferase dUTP nick end labeling, is a laboratory technique used to detect DNA fragmentation resulting from apoptotic signaling. It works by labeling the ends of broken DNA strands, allowing researchers to identify and quantify cells undergoing programmed cell death, which can be important in studies of diseases like cancer or conditions affecting hair follicles, such as alopecia.

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community 9 months fin+microneedling/2 years min, looks like there’s a light at the end of the tunnel

in Progress Pictures 100 upvotes 1 year ago

User shared 9-month progress with finasteride and microneedling, and 2-year progress with minoxidil for hair loss. Others asked about microneedling tools, routine, and suggested micro fibers for improvement.

community Exosome Hair Rejuvenation (2nd Month UPDATE!)

in Progress Pictures 3 upvotes 1 year ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Why balding gets worse in every generation?

in Chat 81 upvotes 6 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community I regrew my hairline in 2 years. Never give up hope. No transplant involved either.

in Progress Pictures 1079 upvotes 6 months ago

A user shared their 2-year hair regrowth journey using finasteride, ketoconazole shampoo, and a diet change, without a hair transplant. Despite skepticism from others, the user insists the results are natural and encourages consistency and dietary adjustments.

community Q1 2024 is done. And kintor is completely silent about GT20029.

in Research/Science 28 upvotes 8 months ago

The conversation discusses the lack of updates on GT20029 for hair loss treatment, with some users noting recent reports indicating ongoing data collection. There are mentions of other treatments like Pyrilutamide and Minoxidil.

community Have you noticed any difference in mood or energy since being on fin/dut?

in Finasteride/Dutasteride 25 upvotes 1 year ago

Users discuss effects of Finasteride/Dutasteride on mood and energy. Some experience depression, focus issues, and libido changes.

community More great news about SCUBE3... this could be it!

in Research/Science 30 upvotes 1 year ago

SCUBE3 is a potential hair loss treatment that people are hopeful about. It may provide a solution without the side effects of finasteride.

community Meta analysis: Topical or mesotherapy dutasteride is more effective than topical finasteride in the treatment of AGA in men

in Research/Science 19 upvotes 2 years ago

Topical Dutasteride is more effective than topical Finasteride for treating AGA in men, with fewer side effects. Mesotherapy with Dutasteride, administered every 3 months, shows promising results for hair regrowth and maintenance without daily routines or significant side effects.

community 7.5 Month Progress Topical/Oral Minoxidil

125 upvotes 2 weeks ago

The user experienced hair loss after Covid and started using topical minoxidil, then switched to oral minoxidil, along with Nizoral shampoo, ketoconazole shampoo, clobetasol propionate, and clindamycin ointment, which significantly reduced hair loss and scalp issues. Other users suggested trying finasteride for better results.

community How to apply topical Fin with this cone? Feel like everything is stuck on my hair and does not reach my scalp. Feels less effective than oral fin.

in Finasteride/Dutasteride 10 upvotes 2 weeks ago

The conversation discusses switching from oral to topical finasteride for hair loss, with concerns about application methods and side effects like dizziness and low energy. Users suggest mixing finasteride with minoxidil for better scalp coverage and dosage control.

community When Life Starts Taking Your Hair... And Then Your Confidence: A 25-Year-Old’s Battle with Hair Loss

in Chat 124 upvotes 1 month ago

A 25-year-old discusses hair loss and its impact on confidence, considering treatments like finasteride and minoxidil. Recommendations include these medications and lifestyle changes to manage hair loss.

community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 130 upvotes 2 months ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

community I just want to say hello to all my fellow Dutasteride Master Racers!

in Satire 64 upvotes 6 months ago

The conversation humorously discusses hair loss treatments, specifically Dutasteride. Users share experiences and joke about the high cost and effectiveness of the treatment.

community r/Tressless bros in a nutshell

in Satire 639 upvotes 9 months ago

The conversation discusses personal experiences with hair loss treatments, specifically Minoxidil and Finasteride, with some users regretting not starting treatment earlier and others experiencing side effects. Some users are considering or have switched to topical formulations due to side effects from oral medications.

community Shedding on finasteride only; looking for motivation

in Finasteride/Dutasteride 15 upvotes 9 months ago

A user started finasteride for hair loss and saw improvement, but is now experiencing shedding and thinning in new areas. They added Nizoral due to dandruff caused by finasteride. Replies suggest that shedding is normal around 6 months and advise to stick with the treatment.

community TresslessGPT is available to ChatGPT Plus users

in 📣 Announcement 107 upvotes 11 months ago

The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

community Dutasteride 1 year regression. Depressing. (With pictures for proof)

in Progress Pictures 14 upvotes 1 year ago

A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

community About Verteporfin but not about hair

in Technology 16 upvotes 1 year ago

Verteporfin treatment shows promise for hair regeneration and reducing scar tissue in hair transplants. Some users plan to try verteporfin with hair transplants, and it may also be combined with PRP in future experiments.

community What 9 months of daily oral Fin/Min (1mg/2.5mg) progress looks like.

in Progress Pictures 137 upvotes 1 year ago

A user's 9-month progress using daily oral Fin/Min (1mg/2.5mg) for hair loss. The user experienced prolonged shedding but saw significant improvement by month 6, and took the medication in pill form as prescribed by their doctor.

community 8 Months Hair Transplant Progress

in Progress Pictures 152 upvotes 1 year ago

The post is about a user's 8-month progress after a hair transplant at Attica Clinic using 1400 grafts, oral Biotin, Pura D'or Serum, Klorane Quinine Shampoo, microneedling, and daily 5-minute scalp massages. The comments vary, with some praising the results and others criticizing them as unnatural.

community There is news from pyrilutamide?

in Product 32 upvotes 1 year ago

The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

community In Mozambique you need to take finasteride to save your life

in Satire 509 upvotes 1 year ago

The conversation is about hair loss and the specific treatments mentioned are finasteride and minoxidil.

community 2 years of Dutasteride. Not sure if I had proper MPB, or TE following drastic weight loss. But here it is (5 pics from then, and 6 from now).

in Progress Pictures 33 upvotes 1 year ago

User experienced hair thinning after losing 100 lbs and started Dutasteride treatment. They faced side effects like fatigue, brain fog, and insomnia but no erectile dysfunction.

community Maybe he should have tried to discover hair treatments...

in Satire 639 upvotes 1 year ago

The difficulty of finding a solution to male pattern baldness compared to the discovery of quantum physics, and suggestions for treatments such as Minoxidil, Finasteride, and RU58841.

community 1 month and 1 week update, Topical Min and Fin, Nizoral and Microneedling

in Finasteride/Dutasteride 135 upvotes 1 year ago

A user who started using minoxidil and finasteride topically, micro needling weekly, Nizoral twice per week, and switched to sulfate free shampoo and conditioner. The user reported that after 1 month and 1 week of this routine they noticed their hair was thicker and healthier, with less shedding and no more dandruff or itching during workouts.

community Pyrilutamide - anybody getting real gains from it?

in Finasteride/Dutasteride 32 upvotes 2 years ago

People's experiences with Pyrilutamide as a hair loss treatment, including anecdotal evidence of regrowth and reduced scalp itch when used in conjunction with Finasteride and Minoxidil.

community It took 8 months on finasteride before I saw any progress. Progress pictures, advice, and my routine are listed below.

in Progress Pictures 41 upvotes 4 years ago

A user shared their hair loss journey, seeing significant improvement after 8 months using finasteride, minoxidil, dermarolling, and supplements. They went from NW 3 to NW 1.5 and emphasized better sleep.

community Wasn't Breezula supposed to post some results soon?

in Question 18 upvotes 5 years ago

The conversation is about expecting results from Breezula, a hair loss treatment, with no new information released as of April 1st. Some joked it's just onion juice, while another comment suggested a conspiracy to cause baldness.

community SHISEIDO is A Bust...

in Update 25 upvotes 6 years ago

Shiseido's hair loss treatment reported only 5% regrowth, disappointing many. Users discussed other treatments like Minoxidil, finasteride, RU58841, and CB-03-01 as potential alternatives.

community I am not losing my hair (yet) and do not think I will soon, but I am a pre medicine major who has an obsession over stem cells and want to share something with you all. Your future is brighter than you think.

19 upvotes 7 years ago

User hoodoomoovoo discusses their interest in stem cell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.