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30-60 / 1000+ resultscommunity My pick for Topical Finasteride/minoxidil solution application is the droplet with a tweak.
The conversation is about applying topical finasteride and minoxidil for hair loss. OP prefers using a droplet applicator for efficiency, while another user prefers foam to avoid dripping.
community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026
PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.
community Best way to apply liquid topicals (minoxidil, RU58841 solution, etc) especially for thick or long hair, diffuse thinning
Using a blunt tip syringe is an effective method for applying liquid topicals like minoxidil and RU58841, especially for those with thick or long hair experiencing diffuse thinning. The user found significant hair regrowth and increased density after using these topicals for less than three months.
community Nuclear topical fin formulation?
The conversation discusses a hair loss treatment involving oral minoxidil, topical finasteride, and a custom topical formulation with minoxidil, cetirizine, finasteride, progesterone, and hydrocortisone. The user seeks advice on the effectiveness of these ingredients for diffuse thinning.
community 13 months TOPICAL ONLY progress! (Diffuse thinner)
The conversation is about a user's progress in treating diffuse hair thinning using a topical regimen including finasteride, minoxidil, ketoconazole, microneedling, saw palmetto, collagen, and vitamins, along with lifestyle changes. The user plans to switch from topical to oral finasteride for potentially better results.
community Reverse hair loss w/ fecal transplants lol?
Fecal microbiota transplants (FMT) are discussed as a potential treatment for hair loss, but they are not effective for androgenic alopecia. The conversation also mentions that FMT is FDA-approved for recurrent C. diff infections and is being explored for other conditions.
community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle
The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
community 📈 Solving for very low dose topical finasteride titration intervals
The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.
community If apply topical fin goes systemic then does it matter where I apply it on the scalp?
The conversation is about whether topical finasteride and minoxidil need to be applied directly to the affected areas of the scalp or if they can be spread through blood vessels. It also asks how long topical finasteride remains on a pillow.
community Help On Topical Finasteride 0.3%
A user is seeking advice on a new topical hair loss treatment containing Minoxidil 3%, Finasteride 0.3%, Progesterone 1%, Hydrocortisone butyrate 0.1%, and Ketoconazole 0.5%. They are concerned about the systemic absorption of Finasteride and plan to do blood tests and a spermiogram before starting.
community Do the more newer gen topical retinoids e.g. tazarotene outperform tretinoin in inducing follicular sulfotransferase activity?
Tazarotene may outperform tretinoin for hairline treatment with minoxidil, but lacks evidence. Tretinoin is recommended for the scalp, while tazarotene can be used on the face.
community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
community Scalp Skin Barrier Health and Hair Follicle Cycling: A Potential Overlooked Connection
The conversation discusses the importance of scalp skin barrier health in hair follicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.
community What factors cause more regrowth for MTF people with hormone replacement therapy?
Hair regrowth in transfems is more effective due to hormonal changes, specifically estrogen, which keeps hair in growth phase longer. Treatments mentioned include anti-androgens, sex hormones, and DHT blockers like finasteride.
community How to layer multiple topicals? (tretinoin, topical min, topical fin)
The user plans to use a combination of tretinoin, topical minoxidil, and topical finasteride for hair loss treatment. They seek advice on application order, timing, and tretinoin dosage.
community Any positive responses for Diffuse Thinner with Retrograde using Fin/Min/Dut
People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.
community are all vellus hairs likely to go terminal if fin/dut + min + tret are used long enough?
The user has been using a combination of finasteride/dutasteride, minoxidil, tretinoin, and hydrocortisone with microneedling and ketoconazole shampoo for hair loss. They are asking if the baby hairs growing will turn into terminal hairs with continued treatment.
community Wouldn’t it be funny if there already was a drug that existed which reactivated sleeping follicles? It would be our own version of Ozempic
PP405 shows promise for reactivating hair follicles, with potential maintenance using 5AR inhibitors. Current treatments like Minoxidil and finasteride are effective but have limitations, and there is hope for more effective solutions in the future.
community TH07 by Triple Hair entering phase III trial
A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.
community New growth, not sure from which treatment(stem cells or RU58841), hair line extending!
The user experienced new hair growth after switching from oral finasteride to topical RU58841 with minoxidil and undergoing stem cell therapy. They noticed new hairs at the hairline and temples, but are unsure which treatment is responsible.
community Hair follicle neogenesis
A user plans to experiment with creating new hair follicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.
community Help in figuring out carrier for topical finasteride!!!
OP is considering using Stemoxydine or the Ordinary Multi Peptide Hair Serum as a carrier for topical finasteride, avoiding minoxidil due to palpitations. They plan to crush finasteride pills into a 30 ml solution.
community Last resort attempt. Studies suggest that finasteride topically actually inhibits up to 52% scalp dht which is smiles to dut 0.5mg daily. This solution contains: fin, min, melatonin and progesterone. Trial started today.
The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.
community DIY tropical finastride liposomal
Topical finasteride at 0.1mg reduces hair loss by 70% but higher doses cause side effects. Some users suggest making liposomal finasteride at home for better results.
community Even if the new drugs succeed, how are we gonna apply so many topicals?
New hair loss treatments like GT20029, Clascoterone, and PP405 are being discussed, with concerns about how to apply multiple topicals alongside existing treatments like minoxidil and finasteride. Suggestions include creating a routine, mixing treatments, or minimizing redundancy in treatment stacks.
community Looking at starting RU from ROK Chem
The user has been using finasteride, minoxidil, and dermastamping for hair growth but has seen a plateau in results. They are considering adding a product called Follicium, containing RU58841 and other ingredients, to their regimen while transitioning from finasteride to dutasteride.
community latanoprost, minoxidil and biotin 3/20/23 vs 5/21/23 same spot
Hair loss treatment with latanoprost, minoxidil, and biotin showed progress. Latanoprost, a glaucoma drug, stimulates anagen phase and increases conversion of vellus hair to terminal hair.
community Going from near slick to cowlick
The user experienced significant hair regrowth using finasteride, minoxidil, and a 4,000-graft hair transplant performed by Dr. Nader in Reynosa, Mexico. The results were natural-looking, and the user plans a second transplant for additional density if needed.
community A non-responder revisiting Minoxidil with Follica FR5 / FR10 / FR15
The user discusses using Follics FR5, FR10, and FR15, which combine Minoxidil, Adenosine, Procapil, Azelaic acid, and Procyanidin B2, to address hair loss. They have previously used Minoxidil, Finasteride, and Dutasteride with varying success.