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      community Dr. Bloxham Verteporfin Update #5

       80 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. It also mentions an update on Dr. Bloxham's Verteporfin treatment.

      community Some good news for the future.

       98 upvotes 1 year ago
      PP-405, a potential hair loss treatment, shows promise in stimulating dormant hair follicles and may help with various hair loss types. Current treatments like Minoxidil are still recommended as PP-405 is in early trials and may take years to become available.

      community PP405 will be available on Everychem soon apparently

       97 upvotes 1 year ago
      PP405 is a potential hair loss treatment, but its safety and effectiveness are uncertain. Users advise caution and suggest waiting for more data before purchasing unverified versions.

      community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

      in Treatment  5 upvotes 5 months ago
      A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

      community Can we get a reality check on PP405?

       79 upvotes 11 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community Is there any new drug that looks promising ?

       26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community A New Hair Loss Drug Could Cure Balding and Reverse Graying

       367 upvotes 10 months ago
      ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.

      community Where can I sign up for hair cloning clinical trials?

       4 upvotes 2 years ago
      The conversation is about a user interested in participating in hair cloning clinical trials due to their fine hair and previous positive experience with clinical trials. They are seeking information on how to volunteer for such trials.

      community SCUBE 3 (the last hair bender)

       2 upvotes 1 year ago
      SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinical trials. No specific updates or new information are provided in the conversation.

      community The case for 5ARI-free hair transplants: Dr. Zarev, Pittella, Sethi, Miln, and future treatments in development

       13 upvotes 10 months ago
      Some individuals experience side effects from 5AR inhibitors like finasteride and are considering hair transplants without these medications, with some opting for surgeons like Dr. Zarev. Others are exploring alternative treatments and waiting for new medications in development, while some discuss managing side effects through lifestyle changes or additional medications.

      community (MTF 35) 20 Months Feminizing HRT

      in Transgender  18 upvotes 7 months ago
      A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

      community Now That PP405 Hype is Gone What is Everyone Coping with as the Next Cure?

       41 upvotes 1 month ago
      People are discussing various hair loss treatments, including finasteride, minoxidil, RU58841, and new potential treatments like vdphl01, ABS-201, and KX-826. Some express hope in future developments like hair cloning and CRISPR, while others emphasize acceptance and sticking with current treatments.

      community Won’t pp405 and gt20029 be patented and be almost unreasonably expensive

       29 upvotes 1 year ago
      Concerns about the potential high cost of new hair loss treatments, pp405 and gt20029, were discussed, with some users willing to pay a premium if they are effective. Alternatives like finasteride and minoxidil are mentioned as current, more affordable options, and there is speculation about future generic versions and black market availability.

      community How promising is kintor pyrilutamide?

      in Treatment  13 upvotes 4 years ago
      The conversation discusses the potential of kintor pyrilutamide as a promising treatment for hair loss, with ongoing trials in various phases. There is skepticism due to delays in trial results, but the company is actively pursuing further trials.

      community Clascoterone for hair loss. Promising study.

       11 upvotes 9 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community 25 F Diagnosed With Telogen Effluvium?

       5 upvotes 10 years ago
      A woman experiencing hair loss for over three years was diagnosed with female pattern hair loss and later with telogen effluvium, leading to a temporary stop of spironolactone treatment. She questions the diagnosis and treatment as her hair continues to worsen despite being advised to wait it out.

      community JXL082 is not PP405 and Everychem followed the wrong lead

       41 upvotes 1 year ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community NW5.5 testing stack of most common "alternative" treatments and methods

       7 upvotes 5 months ago
      A 43-year-old male with advanced hair loss is experimenting with alternative treatments, including red light therapy, microneedling, scalp massages, an oil mix, and ketoconazole shampoo, after previously experiencing side effects from finasteride and minoxidil. He noticed some minor changes with red light therapy but remains skeptical about significant improvement.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

       6 upvotes 11 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community About Pyrilutamide Phase II US Trial

      in Research/Science  11 upvotes 3 years ago
      The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

      community Let's talk about Tsuji and Shiseido

       4 upvotes 8 years ago
      The conversation discusses hair loss treatments, focusing on Tsuji's hair cloning and Shiseido's RCH-01, with skepticism about their effectiveness on humans. It compares these to PRP, noting PRP's higher efficacy in studies.

      community 24F - AGA & TE since 14. Is this regrowth for sure?

       2 upvotes 8 months ago
      A 24-year-old woman with AGA and TE since age 14 is questioning if her hair is regrowing or breaking. She has been using minoxidil consistently since September 2025, along with caffeine and ketoconazole shampoos, rosemary oil, and saw palmetto, and has improved her overall hair care routine.

      community Dogan Turan vs Bruno Pinto please i need your suggested

       4 upvotes 1 year ago
      The user is considering a hair transplant and is using topical finasteride, minoxidil, antiandrogens, ketoconazole shampoo, and serenoa repens. They are deciding between surgeons Dogan Turan and Bruno Pinto, and are concerned about the technique and potential complications due to diffuse hair loss.