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GlossaryTissue Damage

harm to body's tissues affecting function and structure

Tissue damage refers to harm or injury inflicted on the body's tissues, which can include skin, muscles, nerves, and internal organs. This damage can result from various causes such as physical trauma, infections, chemical exposure, or autoimmune reactions. In the context of hair and alopecia, tissue damage to the scalp can disrupt hair follicles, potentially leading to hair loss.

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community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 69 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community 48 days of Fin, Min, and Dermaroller

in Progress Pictures 1742 upvotes 1 year ago

The user has been using finasteride for hair loss for 2-3 years, and added 5% topical minoxidil and daily 1.5mm dermarolling to their routine 50 days ago, which resulted in significant hair growth. The user recommends dermarolling along with minoxidil and finasteride for better results.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 8 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.

community Ru58841 ruined my life. Here’s why.

in Product 126 upvotes 2 years ago

User experienced shortness of breath, high blood pressure, red eyes, and eye floaters after using RU58841 for hair loss. They warn others to avoid RU58841 and stick to finasteride, minoxidil, and dutasteride.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community 11 months Fin and 4 months microneedling

in Progress Pictures 73 upvotes 10 months ago

The user reported positive hair regrowth after 11 months on finasteride and 4 months of microneedling. Opinions in the conversation vary, with some endorsing microneedling as effective and others emphasizing finasteride as essential, while acknowledging that treatments may not work for everyone.

community 5 months of oral minoxidil and oral dutasteride.

in Progress Pictures 157 upvotes 6 months ago

The conversation discusses the positive effects of taking 5 mg oral minoxidil and 0.5 mg oral dutasteride every other day for hair loss, with one user reporting thicker beard and eyebrows and improved appearance. Another user expresses frustration about not being able to access the treatment in Germany, while a different user mentions experiencing no side effects.

community Should I give minoxidil a try or should I wait to see if I can get any more results from my regimen (fin, Ru58841, microneedling) almost at the 1year mark since starting also wondering if I can mix my ru58841 powder into minoxidil and just use that as my solvent

in Minoxidil 53 upvotes 1 year ago

The conversation discusses whether to add minoxidil to an existing hair loss treatment regimen that includes finasteride, RU58841, and microneedling. Some users suggest trying minoxidil and monitoring for side effects, while others advise waiting to see if current treatments improve results after one year.

community Could microneedling for the next 5 years cause any permanent damage?

in Microneedling 22 upvotes 1 year ago

Microneedling for hair loss and its potential long-term effects. Some users believe it can cause fibrosis and scar tissue if done too frequently or deeply, while others claim it has improved their hair loss when done correctly. There is limited scientific research on the topic.

community Injured temple with derma rolling

in Microneedling 2 upvotes 1 month ago

OP injured their temple using derma rolling and tretinoin, causing peeling and potential hair follicle damage. Users suggest the injury might be permanent, possibly resulting in scar tissue where hair won't grow.

community Does microneedling damage scalp?

in Research/Science 12 upvotes 8 months ago

Microneedling does not prevent future hair transplants, but some surgeons report the skin becomes "harder" in treated areas. There is no clear evidence to confirm this effect.

community Hair theory Scar tissue and Verteporfin

in Chat 26 upvotes 5 months ago

A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 15 upvotes 4 years ago

Finasteride can cause gynecomastia, which may be reversible by stopping the drug and using selective estrogen receptor modulators (SERMs) like tamoxifen. Lifestyle changes such as weight loss and avoiding alcohol can also help, but surgery may be needed if the condition persists.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 5 months ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Hi i saw someone posting this and im just retyping it again tbh does anyone know whats the reason behind this!

in Chat 6 upvotes 10 months ago

Minoxidil helps hair growth on both scalp and face, but stopping it leads to hair loss on the scalp, not the face. The user questions why scalp hair can't be maintained with finasteride or androgen blockers after stopping minoxidil, despite these treatments reducing DHT damage.

community Verteporfin day 119 update - donor hair regeneration human trial

in Research/Science 147 upvotes 2 years ago

A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

community Case study: 2mo update 1.5mm microneedling + Minox, no fin. Added Nizoral.

in Microneedling 8 upvotes 4 years ago

The user reports some hair regrowth after two months of using 1.5mm microneedling with Minoxidil and Nizoral shampoo. They note reduced pain and skin flaking, attributing changes to skin thickening and collagen induction.

community Hair Loss Treatments On a Budget, A Scientific Approach (Topical Finasteride, Minoxidil, Tretinoin, Castor + Peppermint Oil and more)

in Finasteride 10 upvotes 8 years ago

The conversation discusses affordable hair loss treatments, including topical finasteride, minoxidil, tretinoin, and natural remedies like castor and peppermint oil. Specific treatments for hair loss are the focus.

community What's the general consensus on microneedling here?

in Microneedling 21 upvotes 5 months ago

The conversation discusses microneedling for hair loss, focusing on optimal needle depth and frequency. Users report varying practices, with some using Minoxidil after microneedling and others suggesting different depths and frequencies based on personal tolerance.

community I enjoy taking finasteride every day

in Finasteride/Dutasteride 241 upvotes 6 months ago

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

community What are the chances I do more harm than good with microneedling?

in Microneedling 18 upvotes 1 year ago

The user reported progress with hair regrowth using a topical solution combining finasteride and minoxidil, but experienced scalp irritation which improved after adjusting the treatment. They are considering microneedling but are concerned about the risk of scarring.

community Why plain Azelaic acid is a safe and effective product for hairloss that makes Finasteride an obsolete treatment for male pattern baldness.

8 upvotes 10 years ago

The conversation discusses the effectiveness of Azelaic acid for hair loss, suggesting it may make Finasteride an outdated treatment for male pattern baldness. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Will hair regenerate if androgen receptors are nuked?

in Research/Science 9 upvotes 1 year ago

Treatments for hair loss, such as using AR receptor blockers and degraders, to see if follicles can regenerate in the long term. The conversation also discusses how hair transplants could be a potential solution.

community Did anyone of you see significant improvements after adding dermarolling to the already ongoing minoxidil treatment?

in Microneedling 35 upvotes 3 months ago

Users discussed adding microneedling to minoxidil treatment for hair loss. Some saw improvements, especially when combining microneedling with minoxidil and finasteride, while others did not notice significant changes.

community Taurine supplements work for hair growth?

in Product 8 upvotes 6 months ago

The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

community 1 yr in! Fin/Min/Dermaroll/Keto

in Progress Pictures 78 upvotes 1 year ago

The user, InternationalTutor92, shared their progress pictures after using a combination of finasteride, minoxidil, keto shampoo, and dermarolling for a year. They mentioned that their hairline on the left side has improved, and they did not experience any side effects from the treatments.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 737 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community 3 months on minoxidil and microneedling alone

in Progress Pictures 632 upvotes 2 years ago

This conversation was about a user's progress pictures from using minoxidil and microneedling to treat hair loss. Other users suggested finasteride as an additional treatment, while cautioning that the drug could have permanent side effects.