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      community Has Anyone Gotten Results With TH16?

       4 upvotes 3 years ago
      The conversation discusses using TH16, a topical melatonin with resveratrol, and stemoxydine for hair maintenance, avoiding finasteride and minoxidil due to side effects. The user is considering a low-dose topical finasteride despite sensitivity.

      community PP405 Updates Feel Like Breadcrumbs at This Point

       11 upvotes 3 months ago
      PP405 updates are seen as vague and lacking substance, causing frustration among users. Some users report positive effects from using minoxidil and dutasteride, while others remain skeptical about new treatments.

      community Losing ground on 3x a week finasteride

      in Finasteride/Dutasteride  3 upvotes 8 months ago
      The user is experiencing hair loss despite using finasteride three times a week due to side effects and is considering alternatives like topical finasteride, estrogen blockers, or dutasteride. They are also interested in potential treatments like GT20029 and pyrilutamide.

      community Finasteride daily for 10 months, no progress.. switching to dut

       13 upvotes 10 months ago
      A user has been using finasteride and minoxidil for hair loss without success and is considering switching to dutasteride. They are concerned about low DHT levels and are seeking advice on how to implement dutasteride effectively.

      community can someone confirm the dosage math for making RU58841

      1 year ago
      The conversation confirms that to make a 5% RU58841 solution, 1.5 grams should be added to 30 mL of KB Solution. The discussion involves calculating the correct dosage for hair loss treatment.

      community GT20029 and PP405 the new fin and min that we been waiting for ?

       36 upvotes 1 year ago
      PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

      community Fin 1mg and Min 2.5 mg for 2 years this month

      in Progress Pictures  69 upvotes 7 months ago
      The conversation is about hair loss treatments, specifically the use of 1 mg finasteride and 1.5 mg oral minoxidil over two years, with consideration of a future hair transplant and possibly switching to dutasteride. Users discuss their own experiences and suggest trying different treatments like minoxidil 5%.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

       6 upvotes 11 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

       124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community 0.5mg dut against 1mg fin for a first timer?

      in Finasteride/Dutasteride 1 year ago
      A 28-year-old male considering hair restoration is deciding between starting with 0.5mg dutasteride or 1mg finasteride, with finasteride being the typical starting point due to fewer and shorter-lasting side effects. The options also include minoxidil and biotin.

      community Switching from 5% to 2% minoxidil

      in Minoxidil  5 upvotes 5 months ago
      The user switched from 5% to 2% minoxidil due to a purchasing mistake and is concerned about potential hair loss or shedding. Suggestions include using 2% minoxidil more frequently or in larger amounts to compensate.

      community Losing ground on dut for 1.5y daily

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user has been using 0.5mg Dutasteride daily and topical Minoxidil but is experiencing worsening hair density and is considering switching to Finasteride, increasing the Dutasteride dose, or adding RU58841. They are also considering microneedling and have concerns about the effectiveness of generic Dutasteride compared to branded versions.

      community Doubtful of RU58441's negative effects

      in Research/Science  2 upvotes 1 year ago
      RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

      community 3-year fin/min plateau broken? Crown progress update (May 2025 – Present)

       50 upvotes 1 month ago
      The user experienced significant hair regrowth after adding GHK-Cu injections to their existing treatment of topical finasteride and oral minoxidil, breaking a long plateau. They are curious if others have had similar experiences with adding new treatments to their regimen.

      community Low Dose Naltrexone For Inflammatory Hair Loss

       10 upvotes 1 year ago
      Low Dose Naltrexone (LDN) may reduce inflammation in alopecia conditions. It is discussed as a potential adjunct treatment with finasteride or dutasteride for androgenic alopecia.

      community Federal Grant Cuts have impacted PP405 related research

       459 upvotes 1 year ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community Dutesteride time at which maximum serum DHT is supressed?

       5 upvotes 3 years ago
      Maximum serum DHT suppression for finasteride occurs at 8 hours, while for dutasteride, it occurs within 1 to 2 weeks with daily dosing. Dutasteride mesotherapy will be followed by blood tests to check serum DHT changes.

      community Ferritin, iron and testosterone

       4 upvotes 5 months ago
      Dutasteride may affect testosterone levels, leading to high ferritin and iron levels, which can cause hair loss. High ferritin might be linked to past heavy drinking or hemochromatosis.

      community Fin 0.025% 1ml Daily. Now Rapidly Thinning My Third Month

      in Progress Pictures  14 upvotes 8 months ago
      The user experienced initial success with topical finasteride 0.025% and melatonin but noticed rapid hair thinning after three months. They are considering switching to a higher dose of topical finasteride or oral finasteride, as advised by others, while being cautious about potential side effects.