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      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 3 months ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.

      community GT20029 Anageninc Market Availability

      in Research/Science  165 upvotes 1 year ago
      The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

      community Help! Gyne after 20 years of taking Dut

      in Finasteride/Dutasteride  39 upvotes 3 months ago
      A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.

      community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

      in Finasteride/Dutasteride  123 upvotes 6 months ago
      The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

      community Bryan Johnson’s Hairloss Regimine

      in Research/Science  26 upvotes 1 year ago
      The post is about Bryan Johnson's hair loss regimen, which includes dutasteride mesotherapy, minoxidil, microneedling, and red laser therapy. The conversation includes discussions about the effectiveness of topical dutasteride and speculation about whether Bryan Johnson has had a hair transplant.

      community So depressed and upset with how much progress I’ve lost

      in Chat  47 upvotes 1 year ago
      A 20-year-old started taking finasteride for hair loss at 18, saw improvement, but developed erectile dysfunction (ED) after taking accutane. Despite stopping both medications, ED persisted, and hair loss worsened. Advice given includes considering tadalafil for ED, resuming finasteride, using minoxidil, and addressing psychological factors through positive thinking and lifestyle changes.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community My Progress - 56 y/o with NW7 hairloss

      in Progress Pictures  70 upvotes 3 years ago
      A 57-year-old man with severe hair loss since age 14 tried various hair loss treatments over two years, including finasteride, dutasteride, minoxidil, and supplements, with some minor regrowth. He also experimented with topical treatments and microneedling, but results were not cosmetically significant.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Finasteride before/after 1,5 year

      in Progress Pictures  215 upvotes 11 months ago
      A user shared their positive experience with finasteride over 1.5 years, noting significant hair regrowth and no side effects. They also mentioned unsuccessful attempts with minoxidil and are considering a hair transplant to improve their hairline.

      community Minoxidil + Gym + Cutting. Is it bad?

      in Minoxidil  38 upvotes 1 year ago
      A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  135 upvotes 2 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community Dutasteride is for Young Hair Loss Suffers

      in Finasteride/Dutasteride  104 upvotes 2 months ago
      Dutasteride is discussed as a treatment for young hair loss sufferers, with mixed experiences regarding side effects and effectiveness. Some users report positive results with Dutasteride, while others prefer Finasteride or Minoxidil due to fewer side effects.

      community 1 month of using fin, so happy

      in Progress Pictures  863 upvotes 3 months ago
      User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 7 months ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community Finasteride won’t make all your problems go away

      in Finasteride/Dutasteride  323 upvotes 11 months ago
      A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community The truth about Dutasteride (w/ sources)

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.