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How androgens, including testosterone, can cause hair follicles to miniaturize in people with sensitivity to androgens, and treatments such as finasteride, dutasteride, minoxidil, RU58841, or fluridil may be used in combination for long-term treatment.

A user experienced mild side effects from 0.5mg finasteride daily, including increased estradiol and minor gynecomastia. They are considering taking a low dose of exemestane to reduce estrogen levels.

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

Hair loss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hair loss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

Dutasteride is a stronger 5AR inhibitor than finasteride and can significantly lower DHT levels. Reduced doses of dutasteride may lower side effects.

People on testosterone replacement therapy (TRT) with aggressive androgenetic alopecia (AGA) discuss using Dutasteride or Finasteride, sometimes combined with topical treatments like RU58841 or CB-03-01 (Breezula), to prevent hair loss. Concerns about side effects and costs of certain treatments are mentioned, with one individual sharing their experience of slowed hair loss using Finasteride alone.

Gym and creatine can cause hair loss by increasing testosterone and androgenic activity. DHT blockers may help some, while others need androgen suppression with topical AA like RU or Pyri.

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

17-alpha-estradiol may work for hair loss by inhibiting 5-alpha reductase, similar to finasteride. It might lower testosterone in the scalp, reducing DHT conversion.

Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.

The user shared their personal experience with hair loss, hormone imbalances, and treatments including testosterone boosters, natural estrogen blockers, and DHEA. They suggest that low-dose finasteride and natural hormone therapy could reduce hair loss with fewer side effects.

The user, Salt_Ad6339, shares their positive experience with hair regrowth after using minoxidil and finasteride for a year, along with microneedling. However, they also mention experiencing chest/nipple pain and suspect it may be a side effect of finasteride. They decide to stop using it for now and see if minoxidil alone can maintain their hair. Other users in the conversation discuss the potential side effects of finasteride and suggest using an aromatase inhibitor to counteract them.

The conclusion of the conversation is that the user started using 5% Minoxidil for hair loss and is happy with the progress. They also mentioned being trans and coming off testosterone, which they believe will help prevent further hair loss. Some users suggested using finasteride as well.

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

The conversation discusses managing estradiol problems during finasteride treatment. Suggestions include stopping finasteride every 3 months for 2-3 weeks or reducing the dosage.

The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

The user achieved significant hair regrowth using Regaine 5% topical minoxidil, dermarolling, rosemary, and pumpkin seed oil. They are considering adding finasteride or dutasteride to their regimen for further improvement.

People are using various treatments for hair loss, including dutasteride, finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. Some also use additional methods like microneedling, vitamins, and oils, with mixed results and personal preferences influencing their choices.

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

Pumpkin seed oil may help hair growth in men with androgenetic alopecia. Treatments discussed include Minoxidil, finasteride, and RU58841.

Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.