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GlossaryTesticular Adrenal Rest Tumors (TART)

benign testicular growths linked to congenital adrenal hyperplasia (CAH)

Testicular Adrenal Rest Tumors (TART) are benign growths found in the testes, often associated with congenital adrenal hyperplasia (CAH). These tumors arise from adrenal-like cells that are abnormally located in the testes and can lead to complications such as testicular pain, infertility, and hormonal imbalances. Regular monitoring and management are crucial for individuals with CAH to prevent or mitigate these issues.

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community Carnitine Tartrate + Potassium chloride + Niacin

7 upvotes 9 years ago

The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

community Hair Regrowth Protocol for the Brothers suffering

in Treatment 57 upvotes 10 months ago

The conversation discusses a hair regrowth protocol involving Dutasteride, Pyrilutamide, Stemoxydine, Minoxidil, Tretinoin, Oral Castor Oil, and L-Carnitine L-Tartrate. Some users are skeptical, particularly about the effectiveness and side effects of oral castor oil.

community Is there a way to boost/enhance the effects of minoxidil?

in Minoxidil 8 upvotes 4 years ago

Enhancing minoxidil effects can involve using penetration enhancers like DMSO, urea, or retinol, and methods like dermarolling and adding substances like biotin and L-carnitine tartrate. Some users suggest trying higher concentrations of minoxidil if lower percentages are ineffective.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community We don’t actually know what’s going on.

in Treatment 212 upvotes 5 months ago

Hair loss treatments vary greatly in effectiveness and timelines, with no guaranteed results. Common treatments mentioned include finasteride, minoxidil, and RU58841.

community 11 months on fin only. Regrowth + thickness

in Progress Pictures 568 upvotes 10 months ago

A user reported hair regrowth and increased thickness after 11 months using finasteride 1mg, taken 3-4 times a week, with noticeable improvement starting around the third or fourth month. No side effects were mentioned, and the user is considering reducing the dosage to find the minimum needed to maintain results.

community Does anyone have any experience being converted to a minoxidil responder after adding tretinoin or stemoxydine?

in Minoxidil 6 upvotes 2 years ago

Minoxidil non-responder seeks experiences with combining tretinoin or stemoxydine for hair loss treatment. Asks if anyone saw results after adding these products.

community Methionine? Glycine?

6 upvotes 8 years ago

The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

community KX-826 Pyrilutamide1% coming soon

in Update 152 upvotes 2 months ago

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

community How can ru-58841 be effective if pyrilutamide failed phase 3 clinical trials?

in Research/Science 10 upvotes 8 months ago

The conversation discusses the effectiveness of RU58841 for hair loss compared to pyrilutamide, which failed to show significant hair regrowth in trials. Some users report personal side effects with RU58841 and question the criteria for success in hair loss treatments.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 158 upvotes 10 months ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Male Pattern Baldness Routine

in Ketoconazole 7 upvotes 3 years ago

An 18-year-old diagnosed with male pattern baldness is using probiotics, saw palmetto, pumpkin seed oil, soy isoflavones, biotin, fish oil, quercetin, a multivitamin, and ketoconazole shampoo. Replies suggest these methods are ineffective and recommend finasteride, minoxidil, and a derma roller.

community 2.5 years of treatment, best decision of my life

in Progress Pictures 8470 upvotes 1 month ago

A user shared their 2.5-year hair loss treatment success using 1mg finasteride daily and switching from 5mg to 2.5mg minoxidil. They reported no significant side effects and emphasized the importance of early treatment.

community Fats on your Head to Stop Hair Loss?

in Research/Science 137 upvotes 8 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Topical quercetin combined with finasteride for max results

in Research/Science 25 upvotes 1 year ago

Combining Finasteride with topical Quercetin, Onion/Garlic juice and Peppermint Oil to reduce Wet Prostate Weight in Rats. Luke10191 asked the user LITUATUI to update them on progress after trying this combination of treatments for hair loss.

community 21 y/o male Fin/min/ketoconazole 3.5 month before and after… 1 mg 3x per week, just recently upped to 1 mg daily. Minoxidil application once before bed and keto shampoo couple times a week. zero sides. Regrowth?

in Is this regrowth? 64 upvotes 1 year ago

A 21 year old male who has been taking finasteride, minoxidil and ketoconazole for 3.5 months with minimal side effects and successful hair regrowth. Genetics also seem to play a role in the user's hair loss.

community Anyone else’s beard took a huge hit on finasteride or dutasteride? Would minoxidl hepl?

in Progress Pictures 105 upvotes 1 year ago

The effects of finasteride and dutasteride on beard growth, whether minoxidil would help with facial hair loss caused by DHT blockers, and anecdotal evidence from users who have experienced either decreased or increased facial hair density while using these treatments.

community 1 month and 1 week update, Topical Min and Fin, Nizoral and Microneedling

in Finasteride/Dutasteride 135 upvotes 1 year ago

A user who started using minoxidil and finasteride topically, micro needling weekly, Nizoral twice per week, and switched to sulfate free shampoo and conditioner. The user reported that after 1 month and 1 week of this routine they noticed their hair was thicker and healthier, with less shedding and no more dandruff or itching during workouts.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 735 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community 1 year fin 1mg and minox. can see some density reclaimed

in Update 562 upvotes 3 years ago

User shared 1-year progress using finasteride 1mg and minoxidil, regaining hair density. Others praised the improvement and asked about side effects and additional treatments.

community I spoke to the Guy who did the Ru58841 (PSK-3841) research

in Research/Science 289 upvotes 3 years ago

The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.