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      community My experience with Alfatradiol so far

      in Treatment  10 upvotes 1 year ago
      User is 16, experiencing hair loss, and using minoxidil and alfatradiol. Shedding decreased, new hairs growing on temples, but unsure if alfatradiol is effective or if future shedding will occur.

      community Minokem-N cotains hydrocortisone?

      in Minoxidil  2 upvotes 1 month ago
      Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

      community Does RU work? I see people buying it and reporting success, but if so why was it discontinued?

      in Treatment  3 upvotes 1 month ago
      RU58841 is a controversial hair loss treatment with mixed reviews; some users report success, often in combination with other treatments like finasteride or minoxidil, while others experience side effects like chest pain. The treatment's discontinuation is speculated to be due to patent expiration and lack of profitability, despite some users continuing to use it as part of a broader regimen.

      community Starting ketoconzole. How much and How many times a week?

      in Ketoconazole  12 upvotes 1 month ago
      A user is experiencing severe dandruff and hair loss, considering using ketoconazole shampoo 2% to manage these issues. They seek advice on application frequency and effectiveness, with suggestions to use it 2-3 times a week and to consider other treatments like finasteride for hair loss.

      community New stack I started this year has ruined my hair

      in Finasteride/Dutasteride  6 upvotes 1 month ago
      Switching from finasteride and topical minoxidil to oral minoxidil and dutasteride worsened hair condition, leading to frustration and heart issues, prompting a return to topical treatments and the addition of tretinoin. Patience and consistency are advised, as these treatments can take years to show results, and abrupt changes may cause shedding.

      community Hairline regrowth without HT, what are my options?

      in Treatment  6 upvotes 2 months ago
      The user is using multiple topical treatments including Minoxidil, RU58841, and Spironolactone, along with supplements, to address hair loss and is considering starting oral Minoxidil. They plan to begin oral finasteride soon after experiencing side effects from topical dutasteride.

      community How to Keep Your Hair on Steroids

      in Treatment  17 upvotes 3 months ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community What Private blood test should I take?

      in Finasteride/Dutasteride  7 upvotes 4 months ago
      A user in the UK seeks advice on blood tests before starting Finasteride and Minoxidil for hair loss. Recommended tests include thyroid function, hormone levels, liver and kidney function, and vitamin and mineral levels.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 6 months ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community 23M losing ground very after seeing improvements

      in Progress Pictures  25 upvotes 7 months ago
      A 23-year-old male was using 0.5 mg of dutasteride daily, 10% minoxidil twice daily for 4-5 months then once daily, and vitamin D for a month for hair loss treatment but saw a decline in results. It's suggested that the decline may be due to reducing minoxidil application to once a day and a doctor's visit is recommended for further advice.

      community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

      in Chat  12 upvotes 10 months ago
      The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

      community First 3 pics are at 6 months .5 mg fin daily, last 3 are 13 months

      in Progress Pictures  75 upvotes 11 months ago
      The user experienced improved hair at 6 months using 0.5 mg finasteride daily but noticed more scalp visibility and potential hair loss at 13 months, questioning if this was due to shedding or the treatment not working. Some respondents suggested the possibility of a shed or scalp inflammation, while others observed improvements or advised checking for underlying scalp conditions.

      community Facing difficulty in applying minoxidil to the scalp as I have long hair.

      in Scalp Massage  11 upvotes 1 year ago
      An 18-year-old male experiencing hair thinning and loss is using oral minoxidil, topical minoxidil, finasteride, and a multivitamin as prescribed by a dermatologist. He's having difficulty applying the topical minoxidil effectively due to his hair length, as he feels a lot of it stays on his hair instead of reaching the scalp.

      community Anger and frustration as I finally learn my diagnosis.

      in Female  6 upvotes 1 year ago
      A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

      community high estrogen levels after 10month fin

      in Finasteride/Dutasteride  9 upvotes 1 year ago
      A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

      community HMI-115 question about potential earliest access

      in Research/Science  9 upvotes 1 year ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community What’s more reliable right now, pyrilutamide or RU?

      in Treatment  15 upvotes 2 years ago
      Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.

      community Dutasteride broked my liver (maybe)

      in Finasteride/Dutasteride  8 upvotes 2 years ago
      A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

      community Hair loss treatment rabbit hole [OC]

      in Satire  317 upvotes 2 years ago
      Hair loss treatments, ranging from topical minoxidil and finasteride to taking hormones such as estradiol or nandrolone, as well as a controversial suggestion of an orchiectomy. A hair system is also mentioned as an alternative solution.