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      community Minoxidil works only with Retinoic acid

       314 upvotes 1 year ago
      Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.

      community Summary of Procapil video by Haircafe

       2 upvotes 1 year ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 1 year ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community Regrowth after 3 months. Min only

      in Is this regrowth?  181 upvotes 1 year ago
      A 38-year-old man is using topical and oral Minoxidil, DHT blocker shampoo, and microneedling for hair regrowth, with plans to add Finasteride later. Many users suggest starting Finasteride or Dutasteride immediately to address the root cause of hair loss, while some express concerns about potential side effects.

      community 3-month progress of hair regrowth

      in Progress Pictures  266 upvotes 1 year ago
      A 29-year-old male shares his 3-month hair regrowth progress using finasteride, minoxidil, and microneedling, reporting no side effects and light initial shedding. He is encouraged by the results and plans to continue the treatment.

      community Why is regrowth impossible for me? What else can I do?

      in Progress Pictures  23 upvotes 1 year ago
      The user is frustrated with hair regrowth despite using finasteride, minoxidil, dutasteride, RU58841, ketoconazole shampoo, and dermastamping. Others suggest improvement, advise against overmedication, and recommend consulting a doctor or considering a simpler regimen or hair transplant.

      community Making your own RT1640 in China

      4 years ago
      RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

      community One year progress pictures! What do yall think?

      in Minoxidil  5 upvotes 5 months ago
      The conversation discusses hair regrowth treatments using finasteride, minoxidil pills, and topical minoxidil, with a focus on the use of a 1.5mm derma roller. Users advise caution with derma rolling, suggesting smaller needle sizes and longer intervals between sessions to avoid skin damage and systemic absorption of minoxidil.

      community Hair Loss "a matter of survival" in South Korea

       335 upvotes 8 months ago
      South Korea's president is advocating for hereditary hair loss to be covered by national health insurance due to its impact on mental health and daily functioning. The discussion highlights the societal pressure in South Korea regarding appearance and the potential benefits of treating hair loss to improve mental health.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 1 year ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

      community FINASTERIDE REVIVING ME FROM THE DEAD

       927 upvotes 2 years ago
      A 17-year-old user reports significant hair regrowth using 1mg finasteride daily and 5% minoxidil once daily. Other users discuss the effectiveness and age considerations of finasteride.

      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 2 years ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community The Real Cause Of Androgenetic Alopecia

       675 upvotes 1 year ago
      Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

      community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

       29 upvotes 2 months ago
      Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 4 months ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community Sooo whats the consensus about pp405 now?

      in Chat  75 upvotes 5 months ago
      PP405 may help with hair regrowth, especially when combined with minoxidil and finasteride, but its long-term effectiveness is unclear. Phase 3 trials are expected to begin soon, with results in a few years.

      community Found a slide summary for PP405

       35 upvotes 5 months ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community Will Pp405 be the Ozempic of bald Guys

      in Research/Science  101 upvotes 7 months ago
      PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

      community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

       89 upvotes 7 months ago
      The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

      community Potential ( but not yet confirmed ) pp405 leak through korean media.

       233 upvotes 10 months ago
      A peptide-based hair loss treatment, PP405, reportedly increased hair density by 62% in 90 days, but these claims are unverified and met with skepticism. Users compared PP405 to Minoxidil and Finasteride, expressing doubts about its effectiveness without more evidence.

      community Creatine Doesn’t Cause Hair Loss: Stop the BS

       137 upvotes 11 months ago
      Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.

      community Federal Grant Cuts have impacted PP405 related research

       459 upvotes 1 year ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.