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    Did you mean Solid-Phase Extraction?
    Glossary Solid-Phase Extraction

    method to isolate specific compounds from a mixture

    Solid-Phase Extraction (SPE) is a method used in laboratories to separate and concentrate specific compounds from a mixture. It involves passing a liquid sample through a solid material (the "solid phase") that selectively adsorbs the target compounds, allowing impurities to be washed away. This technique is widely used in fields like environmental testing, pharmaceuticals, and biochemistry for sample preparation and purification.

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      community Rosemary Oil Takes on Minoxidil in a Viral Hair‑Loss Trial

      14 hours ago
      Rosemary oil can modestly boost hair growth and is gentler on the scalp compared to minoxidil, but it does not outperform minoxidil in direct comparisons. The choice between the two treatments depends on tolerance, cost, and desired improvement.

      community Did My Hair Transplant Fail????

       11 upvotes 1 month ago
      The user is concerned their hair transplant with 1500 grafts may have failed after 10 months, despite using 5% topical minoxidil and 1mg oral finasteride since 2023. Others suggest waiting until 18 months for full results and considering additional treatments like PRP or dutasteride.

      community 2000 beard graft extracted with no visible scar

       213 upvotes 1 year ago
      A user shared their experience with a beard-to-scalp hair transplant, noting no visible scars and improved hair density using finasteride and minoxidil. The conversation discusses the differences between beard and scalp hair, potential changes in hair texture, and the use of beard hair for increased scalp coverage.

      community 7 day hair transplant update - HLC Ankara - How we looking?

       163 upvotes 6 months ago
      A 35-year-old shared a 7-day update on their hair transplant, which involved 3,153 grafts performed by Dr. Elif at HLC Ankara, costing 10,000 euros including accommodations. The user has been on finasteride for over 12 years and opted for a partial shave FUE to address hairline recession and temple peaks.

      community Clearing the air on how non-surgical treatments really work

       16 upvotes 7 years ago
      Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

      community Hair Transplant Results after 6 months . 3500 grafts. NW 6

       373 upvotes 2 years ago
      The user underwent a hair transplant with 3500 grafts and has been using Finasteride and Minoxidil for 5.5 months, seeing some growth. They plan to have a second transplant for the crown area and are seeking opinions on future results and density improvement.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

       737 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community My experience with Harmony Clinic in Cancun, MX

       39 upvotes 4 years ago
      A user had a positive experience with affordable FUE hair transplants at Harmony Clinic in Cancun, Mexico, noting professionalism and good results despite minor issues. The clinic advised against using Minoxidil and Finasteride, and the user was satisfied with the initial results, planning to update progress at 12 months post-op.

      community Creatine & Hair Loss — My Personal Experience (And a Bit of Simple Math)

       71 upvotes 1 year ago
      Creatine may accelerate hair loss in those genetically predisposed, with some users reporting increased shedding while taking it and improvement after stopping. Some users use treatments like finasteride and minoxidil, while opinions on creatine's impact vary.

      community Thoughts on new drug PP405? Already reached phase 2

       26 upvotes 1 year ago
      PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

      community KX-826 Phase 3 Results Are Out

       121 upvotes 5 months ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community GT20029 Phase 2 results are out

      in Treatment  60 upvotes 9 months ago
      GT20029 shows promising results for hair loss treatment, with potential approval in China by 2026 or 2027, but U.S. approval may take longer. It could serve as an alternative to finasteride, with a potentially better side effect profile.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

       124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Phase 3 Study for PP405 officially posted

       43 upvotes 16 hours ago
      PP405 is in a phase 3 trial for hair loss treatment, with the study expected to run until June 2028. Minoxidil and finasteride remain key treatments, with hopes for PP405 to offer a new mechanism of action.

      community PP405 Phase 2a press release with early results

       700 upvotes 1 year ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

       447 upvotes 4 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Thinning again after solid results

      in Finasteride/Dutasteride  4 upvotes 1 month ago
      A 28-year-old using 1mg Finasteride and 2.5mg Minoxidil since September 2024 noticed hair shedding after initial success and is considering switching to Dutasteride. Users suggest it might be a temporary shed, recommend checking for deficiencies, and advise against an immediate switch, suggesting consistency and possibly increasing Minoxidil dosage.

      community Is this solid progress? Any advice will be appreciated

      in Is this regrowth?  185 upvotes 1 year ago
      The user has been using 5% minoxidil and 1mg finasteride since late 2024 and has seen progress in hair regrowth, though they feel it is slowing down. They are considering adding rosemary oil and derma stamping to their routine, with advice suggesting derma stamping once a week at 1mm to 1.5mm.

      community This shedding phase is brutal man…

       590 upvotes 1 year ago
      The user is experiencing a difficult shedding phase after starting a hair loss treatment with oral finasteride, topical minoxidil, and microneedling. Despite the shedding, they remain hopeful for regrowth and plan to continue the treatment, encouraged by others' positive results.

      community Update for PP405 - phase 2b underway

       122 upvotes 1 year ago
      PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

      community KX-826 1% Phase II Results from China Just Dropped

       37 upvotes 1 year ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.
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