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GlossarySkin Thickness

measurement of skin depth, varying across body regions

Skin thickness refers to the measurement of the depth of the skin, which varies across different parts of the body. It consists of two main layers: the epidermis (outer layer) and the dermis (inner layer). For example, the skin on the soles of the feet is much thicker than the skin on the eyelids. Understanding skin thickness is important for medical professionals when diagnosing conditions, planning surgeries, or administering treatments like injections.

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community Tretinoin can enhance the skin permeability of Minoxidil approximately 3-fold at 0.05%[24] and itself has some hair regrowth properties.

7 upvotes 9 years ago

The conversation discusses enhancing Minoxidil absorption for hair loss treatment using Tretinoin and MSM (Methylsulfonylmethane). The user is seeking sources for Tretinoin and mentions MSM's potential to improve the absorption of topical agents.

community Comprehensive Microneedling Guide

in Microneedling 292 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Has anybody tried retinol (not Retin A aka tretinoin) combined with minoxidil?

in Treatment 20 upvotes 2 years ago

The conversation is about someone who had success using retinol with minoxidil for hair growth, but experienced shedding with Retin A (tretinoin). They are asking if others have tried retinol with minoxidil and what their results were.

community Three years + or - on the Big 3. Plus Biotin.

in Progress Pictures 668 upvotes 3 years ago

The conversation discusses a user's hair regrowth over three years using Minoxidil, Finasteride, and a hair transplant, along with Biotin supplementation. Some users question the authenticity of the results and the organization of the before-and-after photos.

community 11 Months Topical Fin 0.3%+Min 6% daily, Last 2 Months Added Min 5% Foam at Night, Late 30s Male Progress

in Progress Pictures 186 upvotes 1 year ago

The user "_Mad_Jack_" shared their progress pictures of using topical finasteride and minoxidil for 11 months. They experienced good hair retention and increased overall hair count, but no regrowth of the hairline. They are considering switching to oral finasteride and microneedling for better results. Testicular pain was a side effect experienced during the treatment. Another user mentioned getting a hair transplant to cover their crown.

community Would Fluridil and Alfatradiol work effectively in conjunction with each other?

in Treatment 9 upvotes 4 years ago

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

community Low-dose oral minoxidil and skin aging

in Minoxidil 7 upvotes 5 years ago

The conversation discusses the use of low-dose oral minoxidil for hair loss and its potential effects on skin aging. Users shared experiences, with some noting side effects like puffy eyelids and dark circles, but no conclusive evidence of significant collagen depletion or increased wrinkles.

community oral minoxidil collagen contradiction

in Minoxidil 13 upvotes 5 months ago

The conversation discusses concerns about oral minoxidil potentially aging the face by affecting collagen, questioning its systemic effects. The user has successfully used topical minoxidil for years and is hesitant to switch to oral minoxidil.

community Under-eye wrinkle appeared after 4 weeks of oral minoxidil use, along with significant dark circles and under-eye puffiness.

in Minoxidil 38 upvotes 1 year ago

The user's experience with oral minoxidil, which resulted in under-eye wrinkles; other users sharing their experiences and advice regarding hair loss treatments such as topical minoxidil, finasteride, RU58841, and collagen supplementation.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community 6 months on topical dut (album linked)

in Progress Pictures 24 upvotes 2 years ago

The post and conversation are about a user's 6-month progress using topical dutasteride, 8% minoxidil, tretinoin, 2% ketoconazole shampoo, microneedling, oral finasteride, pumpkin seed oil, Vitamin D3, a men's multivitamin, rosemary oil, and 5% minoxidil foam for hair loss treatment.

community My Testosterone results before and after Finasteride

in Update 146 upvotes 3 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community Topical fin and min and swallowing semen

in Finasteride/Dutasteride 118 upvotes 5 months ago

A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.

community Has anyone ever tried using (all topicals) finasteride + minoxidil + rosemary oil + castor oil + stemoxydine all over the course of a few months/years?

in Treatment 3 upvotes 7 months ago

The user is using topical finasteride and minoxidil for hair loss and is considering adding rosemary oil, castor oil, and stemoxydine to their routine. They are asking if anyone has experience with this combination or a similar one.

community How possible is temple regrowth really?

in Minoxidil 48 upvotes 8 months ago

A person started using finasteride, minoxidil, and dermarolling to regrow hair at the temples and is asking if it's possible. Some users report temple regrowth is possible with these treatments, while others find it challenging, and advise consistency and patience with treatment.

community An idea that I came up with recently💡

in Satire 289 upvotes 1 year ago

User suggests rotating scalp 180 degrees to address hair loss. Others discuss sanity, ethics, and similar procedures like scalp reduction and hair transplants.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community Finasteride, dutasteride, and oral min- My experience

in Finasteride/Dutasteride 126 upvotes 3 years ago

User took Fin for 3 years, Dut for 7 months, and oral Min for 2 months without side effects. Fin stopped hair loss for 2 years, Dut maintained hair, and oral Min regrew thinning hair.

community I am putting my hair loss treatment on hold until my mental health is better.

in Update 21 upvotes 2 months ago

OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.

community 1 month of using fin, so happy

in Progress Pictures 864 upvotes 3 months ago

User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

community Before, and my last 3 hair styles over 2 years. (Hair system)

in Hair Systems 538 upvotes 4 months ago

A user shared their experience with hair loss, initially using finasteride and minoxidil without satisfactory results, and later switching to hair systems, which they plan to use indefinitely. The user and others discussed the positive reactions, maintenance, and normalization of hair systems for men.

community Is this broscience? From More Plates, More Dates

in Research/Science 22 upvotes 8 months ago

The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 122 upvotes 11 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community If anyone else feels like they’re too far gone for a hair transplant or can’t tolerate finasteride, I highly recommend trying a hair system! You have nothing to lose and it can change your life. I understand the worries and concerns, as I was very nervous/scared before taking the leap. AMA

in Hair Systems 394 upvotes 1 year ago

The conversation discusses the use of hair systems as a solution for hair loss. Users share their experiences, highlighting the natural look, confidence boost, and maintenance requirements of hair systems, while also addressing concerns about cost, stigma, and potential drawbacks.

community Testosterone and hair loss seeming irrelevance

in Research/Science 82 upvotes 1 year ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community 15ish months results. Fin plus Min

in Progress Pictures 481 upvotes 1 year ago

CraigMeyerShirtPants used oral finasteride for 15 months and topical minoxidil for 6 months, seeing significant hair growth after cutting hair 4 months ago. Users congratulated and asked about age, brand, and side effects.

community Overwhelming amount of anti-androgens

in Female 1 year ago

The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

community Hair Tattoo as a substitue to hair transplant

in Transplants 517 upvotes 1 year ago

A hair tattoo substitute for a hair transplant, which many people felt was not a good idea. Several treatments were suggested as alternatives, such as Scalp Micro Pigmentation (SMP) and wigs.

community Anyone here going the “natural” route?

in Scalp Massage 48 upvotes 2 years ago

People discussing their experiences with natural treatments for hair loss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.