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      community Trying to understand finasteride side effects and post finasteride syndrome

       70 upvotes 5 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community Estradiol mesotherapy / idea feedback

       5 upvotes 1 year ago
      The conversation discusses using estradiol mesotherapy to replicate hormone replacement therapy results while minimizing systemic exposure. It also covers the use of Spironolactone cream, which reportedly has no systemic side effects, and the potential risks of using bicalutamide and Spironolactone in men.

      community I Get Side-Effects from Anti-Androgens

       8 upvotes 6 years ago
      Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

      community ABS-201 Trial - What should I know going in

      in Research/Science  28 upvotes 6 months ago
      The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.

      community Quercetin got rid of my scalp soreness

       4 upvotes 1 year ago
      Quercetin reduced scalp soreness and may help with histamine-related hair loss. The soreness felt like inflamed follicles beneath the scalp surface.

      community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

       46 upvotes 1 month ago
      Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

      community DHT Itch flareups and information

      in Research/Science  4 upvotes 2 months ago
      DHT itch often occurs in cycles or flare-ups, particularly around the temples and crown. Treatments like finasteride, dutasteride, and topical minoxidil can reduce or eliminate the itch.

      community Hey med experts explain this please??

       7 upvotes 1 year ago
      Finasteride, dutasteride, saw palmetto, caffeine, spironolactone, acetyltetrapeptides, tea tree oil, hydrocortisone, zinc pyrithione, latanoprost, melatonin, marine protein supplements, PRP, microneedling, and valproate are discussed as treatments for hair loss. DHT reduction and inflammation control are key strategies.

      community Is anyone else allergic to Minoxidil

       4 upvotes 2 years ago
      A user experienced a painful rash from both liquid and foam minoxidil, suggesting an allergy to minoxidil itself. They are seeking others with similar experiences.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 1 year ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community Has there been any update or progress on the 3-alpha hydroxysteroid dehydrogenase hypothesis?

       13 upvotes 2 months ago
      The conversation discusses the hypothesis that a lack of the enzyme 3-alpha hydroxysteroid dehydrogenase (3α-HSD) on the scalp may contribute to hair loss by allowing DHT to accumulate. Despite interest in this theory, no recent research has been conducted, and current treatments like finasteride and minoxidil remain the most supported options.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 8 months ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

      community DS Labs SOD suppliments, anyone try them?

       4 upvotes 1 year ago
      The conversation is about trying DS Labs SOD supplements for hair loss, which contain ingredients like Genistein, B-sitosterol, and Biotin. The user is considering adding these supplements to their existing hair care routine.

      community What are the chances of being chosen for PP405 trials?

      in Research/Science  3 upvotes 7 months ago
      The conversation discusses the potential benefits and risks of participating in the PP405 hair loss trials, emphasizing that those using Minoxidil or finasteride are less likely to be accepted. Participants are interested in the trial as it offers hope for effective treatment without the side effects associated with current medications.

      community Is adding RCP(redensyl, capixyl, procapil) over min+fin make sense?

       5 upvotes 1 year ago
      The conversation discusses the effectiveness of adding RCP (redensyl, capixyl, procapil) to a hair loss treatment regimen that includes minoxidil and finasteride. Users share experiences, suggesting RCP may not be as effective as minoxidil, but could be useful for creating topical solutions.

      community Prolactin and E2 high after finasteride

       18 upvotes 2 weeks ago
      A user experienced libido issues after using finasteride for five months, with elevated prolactin and estradiol levels. The discussion includes differing opinions on whether these symptoms are due to hormonal imbalances or post-finasteride syndrome.

      community What is up with all these body dysmorphic posts lately?

      in Chat  49 upvotes 1 year ago
      The conversation discusses concerns about body dysmorphia related to hair loss, with some users expressing frustration over posts claiming treatments like finasteride and dutasteride are ineffective or harmful despite minimal hair loss. It emphasizes the importance of early treatment with medications like finasteride and minoxidil for those experiencing hair loss.

      community MinoxiBoost - SULT1A1 Enzyme booster journey

      in Minoxidil  7 upvotes 2 years ago
      The user has tried topical Minoxidil and oral Minoxidil for beard and scalp hair growth with minimal results, and has been on Finasteride for 7 months with stabilized scalp hair but no facial hair improvement. They are considering using a SULT1A1 enzyme booster to enhance results and are questioning its effectiveness without concurrent topical Minoxidil application.

      community Pp405 phase 2a clinical results

       37 upvotes 1 year ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community PHG Invites

       4 upvotes 10 years ago
      The conversation discusses a community called PHG, which focuses on experimental hair loss treatments and scientific approaches to hair regrowth. It mentions treatments like Minoxidil, finasteride, and RU58841, and highlights interest in new treatments like Setipripant, Histogen, and Replicel.

      community Haunting study is making me considering cycling fin/dut

      in Research/Science  158 upvotes 1 year ago
      Concerns about the long-term effects of dutasteride and finasteride on fertility, with discussions on cycling these medications to mitigate risks. The conversation highlights skepticism about study methodologies and the importance of weighing treatment risks against potential fertility issues.