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The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

A user has been treating hair loss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hair loss, and they are considering other treatments or causes.

The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

The safety and effectiveness of RU-58841 as a hair loss treatment, with some users reporting side effects like chest pains, while others had positive results. The original research on RU-58841 was likely stopped due to financial issues, not safety concerns.

The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.

This conversation is about the user "Such_Ad7910" sharing progress pictures of their hair loss treatments, which include minoxidil and derma rolling. They recently got a prescription for finasteride to further help with their hairline, and multiple people have commented urging them to use it.

A user shared their experience with finasteride, reporting severe side effects like erectile dysfunction and watery semen, which improved after stopping the medication. They emphasized the risks of finasteride and decided not to resume its use despite hair loss stabilization.

A user is experiencing ongoing hair loss despite using 0.5mg dutasteride and 2.5mg oral minoxidil for several years and is seeking advice. Suggestions include ensuring correct diagnosis, checking for other health issues, considering finasteride, trying topical antiandrogens, and consulting a dermatologist.

A user gained 10-12 kg after starting finasteride but found their estrogen levels to be within the normal range. They are concerned about potential gynecomastia but are reassured by their lab results.

A transgender individual is starting spironolactone and estradiol for hormone replacement therapy (HRT) and is considering adding finasteride to help with hair loss. They are also planning to use minoxidil and microneedle, but are unsure if they need to use another anti-androgen or more aggressive treatments. A respondent advises against using pyri and suggests waiting to see if the HRT alone is sufficient before becoming dependent on minoxidil.

User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.

Dutasteride works for most men, but some may experience worsening due to reasons like shedding, paranoia, non-androgenic alopecia, genetic variations, or smoking. Smoking can increase scalp DHT levels and damage follicles.

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.

People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

A user successfully improved their hairline after 15 months using topical minoxidil and dutasteride. Some commenters question the necessity of treatment given the user's original hair condition, while others support early intervention.

Natural remedies like rosemary oil, coconut oil, and onion juice are generally seen as less effective compared to medical treatments like finasteride, minoxidil, and microneedling. Some users believe natural oils can help, but modern medicine is often more reliable.

The conversation discusses the effectiveness of anti-androgens for hair loss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.

A user using finasteride and dutasteride to treat hair loss, but still losing hair rapidly after stopping minoxidil. Replies suggest that the user should try oral minoxidil or switch to dutasteride for better results.

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

User shared personal hair loss treatment results using 0.5mg Fin daily, Min foam once a day, and Keto Shampoo twice a week. Significant improvement was observed, with others impressed and asking questions about the treatment.

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.