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      community I’m an outlier, very sensitive to Saw Palmetto/Fin

       4 upvotes 5 years ago
      The user experienced sensitivity and side effects from finasteride and Saw Palmetto, leading to swollen and sensitive breasts, and decided to stop finasteride after two weeks. They are now trying Saw Palmetto, Biotin, and Ashwagandha, while others in the conversation discuss their own experiences with hair loss treatments like minoxidil and finasteride.

      community topical cetirizine to control scalp inflammation

       4 upvotes 4 years ago
      The user applies a topical solution containing minoxidil, finasteride, dutasteride, retinoic acid, and hydrocortisone to address scalp inflammation and is considering adding cetirizine to the mix. They are calculating the correct amount of cetirizine to add to their formula and have paused this approach to retry oral minoxidil.

      community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

       17 upvotes 4 years ago
      People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

      community Hormone tests to decide on oral fin

       4 upvotes 1 year ago
      The conversation discusses starting low-dose oral finasteride for hair loss, considering hormone levels and potential side effects like gynecomastia. Suggestions include using DIM for estradiol, vitamin B6 for prolactin, and lifestyle changes to optimize hormone profiles before starting treatment.

      community Has anyone done research on Absci's AI‑driven antibody platform? Seeking your thoughts!

       4 upvotes 1 year ago
      A user is interested in Absci's AI-driven antibody platform, ABS-201, for treating androgenetic alopecia, which shows promising preclinical results and potential for hair regrowth and pigmentation restoration. However, concerns are raised about the drug's development timeline and its advantages compared to existing treatments.

      community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

      7 months ago
      The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

      community Riken develops new method for culturing hair follicles

       41 upvotes 8 years ago
      A new stem cell method for culturing hair follicles is being developed as an alternative to Minoxidil, finasteride, and RU58841. There are concerns about its cost and accessibility despite plans for commercialization.

      community Decades Update: age 23 to 25 and age 39 to 41

      in Progress Pictures  725 upvotes 1 year ago
      The user started using finasteride at age 23, stopped at 30 to start a family, and resumed at 39 with minoxidil, seeing positive results both times. They successfully had four children after stopping finasteride, noting changes in sperm quality and some side effects upon resuming the medication.

      community A rare case? Or a blind spot? Hair loss caused by low T + e2

      in Chat  10 upvotes 1 year ago
      Low testosterone and estradiol may contribute to hair loss, and blocking DHT without sufficient hormone levels might hinder regrowth. The discussion highlights the importance of hormone balance, with some considering supplements and lifestyle changes to support hair health.

      community Another transplant or SMP? (Not balding)

      in Transplants  23 upvotes 8 months ago
      The user is considering another hair transplant or scalp micropigmentation (SMP) for a congenital bald spot, but previous transplants were less effective due to scar tissue. Suggestions include using hair fibers, changing hairstyles, or doing nothing, as the spot is not very noticeable.

      community Gaining or losing beard on fin

      in Finasteride/Dutasteride  6 upvotes 8 months ago
      Using finasteride may slow beard growth due to reduced DHT, but minoxidil can enhance beard growth. Some users report slower beard growth on finasteride, while others see continued improvement with minoxidil.

      community what is the problem with straight low hairline? Hair transplant question

       6 upvotes 1 year ago
      The user is concerned about having a straight, low hairline after a hair transplant and is unable to take finasteride due to high estrogen and prolactin levels. They have used minoxidil with limited success and are considering further transplants to lower the hairline, while others suggest the risks of using up donor hair too quickly.

      community Are there any alternatives to finasteride?

       6 upvotes 3 days ago
      The user stopped finasteride while trying to conceive and is seeking alternatives to reduce hair loss. Suggestions include continuing minoxidil, using saw palmetto, alfatradiol, clascoterone, KX-826, microneedling, and keto shampoo, but safety during conception is uncertain.

      community 24 weeks of treatment. Best decision of my life

       916 upvotes 1 year ago
      A 32-year-old male used 1.25mg oral finasteride daily and 1ml topical minoxidil twice daily for 24 weeks, experiencing improved skin and hair growth with initial side effects that resolved after three weeks. He plans to try dermastamping to address a stubborn cowlick area.

      community Breezula Phase 3 Results enough for maintenance?

       13 upvotes 4 months ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

       4 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community A New Hair Loss Drug Could Cure Balding and Reverse Graying

       367 upvotes 10 months ago
      ABS-201, a prolactin receptor blocker, shows promise in reversing hair loss and graying, with early success in macaques. Current treatments like finasteride, minoxidil, and RU58841 are still widely used, but new options like PP405 are eagerly anticipated.

      community Warning: Minoxidil usage around pets

      in Minoxidil  454 upvotes 1 year ago
      Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

      community Checking in: is fin and min still the latest science

       9 upvotes 1 week ago
      Finasteride and minoxidil remain the primary treatments for hair loss, with dutasteride being a more potent alternative. New treatments like VDPHL01 and topical antiandrogens are in development.

      community Topical finasteride vs RU58841 vs KX826

       1 upvotes 1 month ago
      The user is considering switching from topical finasteride to RU58841 or KX826 to reduce side effects but decides to stick with finasteride for now. Users discuss the effectiveness and risks of RU58841 and KX826, with finasteride being considered the most reliable option.

      community Minoxidil experiment on single hair follicle

       1689 upvotes 1 year ago
      Minoxidil was applied to a single miniaturized hair follicle over four months, resulting in less miniaturization but not yet terminal growth. The user used a 5% minoxidil solution, specifically the Regaine brand, and observed changes using a handheld WiFi microscope.