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      community Is Keto shampoo 2% even worth starting?

      in Ketoconazole  43 upvotes 3 months ago
      Ketoconazole shampoo is primarily for scalp health and reducing inflammation, not hair regrowth. Combining ketoconazole with finasteride can yield similar results to using minoxidil and finasteride together.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 month ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Dutasteride Literally Saves Your Hair

      in Finasteride/Dutasteride  98 upvotes 6 months ago
      Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

      community I got an idea to cure baldness but i need your help

      in Satire  94 upvotes 1 year ago
      User suggests finding unknown baldness cure by applying random items on scalp and reporting results after 6 months. Various users humorously agree to try different substances, including whale sperm and hydrochloric acid.

      community What makes breezula different than formula 82f?

      in Question  8 upvotes 4 years ago
      Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

      community SAFFLOWER OIL good alternative for Minoxidil?

      in Treatment  1 upvotes 4 years ago
      Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  257 upvotes 1 month ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community Help! Minoxidil or Duta to avoid Shed of long hair.

      in Female  6 upvotes 2 months ago
      The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

      community 3 months fin/min progress (age 31)

      in Progress Pictures  171 upvotes 4 months ago
      A user shared their 3-month progress using 1mg oral finasteride daily and 5% topical minoxidil twice daily, along with Pura D’Or anti-thinning shampoo and a scalp massager. They noticed initial worsening but later saw hair follicle recovery.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 6 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Topical finasteride might be a lie

      in Research/Science 1 year ago
      The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

      community 40 years old. 5 months progress. New hair coming in daily.

      in Progress Pictures  123 upvotes 1 year ago
      The user "mynameisbogus" shared their hair loss progress using various treatments including Dutasteride, RU, oral minoxidil, topical treatments, microneedling, dermastamping, rosemary oil, and scalp massaging. Other users commented on the extensive regimen and expressed their opinions.

      community Why I really believe the tension theory is the cause of MPB

      in Research/Science  70 upvotes 3 years ago
      The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 7 months ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  103 upvotes 9 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Am I the chosen one? Minoxidil experience.

      in Research/Science  25 upvotes 1 year ago
      A user applied Minoxidil foam to their face to grow a beard and experienced increased hair density and darker hair as unintended benefits, despite initially using it for diffuse thinning on the scalp. Another person suggested that the user's heart rate increase might indicate a high conversion rate of Minoxidil to its active form, similar to taking oral Minoxidil.

      community I am having Success with RU58841 and 1mm Derma Roller

      in Microneedling  19 upvotes 2 years ago
      A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

      community My story/timeline/positive experience with Finasteride

       8 upvotes 11 years ago
      A 26-year-old male experienced positive results using 1mg Finasteride daily and 2% ketoconazole shampoo for hair loss, with reduced shedding and scalp itch. He reported no significant side effects and recommends early treatment for those in the initial stages of hair loss.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 2 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.