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      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 8 months ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community I wish I'd kept on treatment 4 years earlier...

      in Chat  28 upvotes 11 months ago
      The user regrets not continuing hair loss treatment with finasteride earlier and plans to restart it along with minoxidil. Another user suggests trying dutasteride and oral minoxidil as a more effective treatment.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  49 upvotes 11 months ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community why hair restoration has not been progressed for last 20 years?

      in Chat  31 upvotes 1 year ago
      The conversation discusses the lack of significant advancements in hair loss treatments beyond finasteride and minoxidil, questioning if hair restoration technology has reached a dead end. Hair transplant technology has improved, but new medications face challenges with market entry, cost, accessibility, and long-term effectiveness.

      community 2 months of topical minoxidil (5%) use and there is a shadow now!

      in Transgender  192 upvotes 1 year ago
      The post discusses the user's experience with topical minoxidil (5%) for hair loss, showing some improvement after 2 months. Suggestions from others include keeping the hair shorter on the sides and back, adding finasteride for better results, and considering a shaved head look, though the latter was debated for its femininity.

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 1 year ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 1 year ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community Selling a premixed KY19382 solution

      in Research/Science  8 upvotes 2 years ago
      The conversation discusses the sale of a premixed KY19382 solution for research purposes, highlighting previous unsuccessful group buys and the formulation process. Prices and purchasing options for KY19382 solutions and powder are provided.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 3 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

      community Thinking about my making own CB-03-01 (Breezula). Thoughts?

      in Treatment  6 upvotes 3 years ago
      The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.

      community Finally about to start Pyriltamide (ONLY Pyriltamide)

      in Chat  63 upvotes 3 months ago
      A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

      community Oral or topical finasteride? .

      in Chat  12 upvotes 3 months ago
      A user is deciding between oral and topical finasteride for hair loss, noting oral finasteride's ease of use but broader effects. Another user simply recommends oral finasteride.

      community Help! Gyne after 20 years of taking Dut

      in Finasteride/Dutasteride  39 upvotes 3 months ago
      A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.

      community Terrible experience with MV Supplements and no support

      in Product  3 upvotes 6 months ago
      A user had a bad experience with MV Supplements when their Pyril powder and ethanol order leaked during shipping, making the products unusable. Despite contacting support and providing evidence, the company's return policy did not allow for a refund or replacement.

      community Minoxidil Finasteride heart problems

      in Update  97 upvotes 6 months ago
      A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.