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RU58841 users report mixed results, with some experiencing no benefits and others noting regrowth but potential side effects. Many prefer finasteride and minoxidil due to better-studied safety profiles.

OP uses multivitamins, collagen, biotin, keratin, omega-3, satin bonnet, dandruff shampoo, oil moisturizer, and sun exposure for hair care. Users suggest adding antioxidants, probiotics, pumpkin seed oil, vitamin D, iron, and dermastamping.

A user shared their 5-month progress using Finasteride (1mg daily) and 3 months on Oral Minoxidil (5mg daily) for hair regrowth, reporting significant improvement and no side effects. They experienced initial shedding with Minoxidil but saw substantial regrowth, encouraging others to try these treatments.

A 42-year-old user shared a 4-month update on their hair regrowth using a "nuclear stack" including oral and topical minoxidil, dutasteride, RU58841, micro-needling, keto shampoo, saw palmetto, biotin, multivitamins, scalp massages, and inversion table. They reported significant progress with minimal side effects and plan to continue the routine.

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

OP uses 1mg finasteride, 2.5mg minoxidil, and 10mg biotin daily, along with a biotin, caffeine, and saw palmetto shampoo. OP noticed results after 5 months, with occasional heart palpitations from minoxidil.

OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

A 28-year-old shared his 2-year hair loss treatment progress using finasteride, minoxidil, dermarolling, and Revita shampoo. He saw significant improvement, especially with minoxidil and dermarolling, and stressed consistency.

OP used finasteride, topical minoxidil, microneedling, and caffeine shampoo for hair loss. After 4 months, they saw progress with new, lighter-colored hairs.

A 24-year-old started losing hair at 17 and began treatment with Dutasteride, Minoxidil, Biotin, and Saw Palmetto shampoo in November 2023. After initial success, hair shedding resumed, leading to concerns about treatment quality and effectiveness; the user plans to consult a dermatologist and consider buying medications directly from a pharmacy.

User is pleased with hair growth results after nearly a year of using Minoxidil and finasteride, despite experiencing shedding phases. They noticed thicker hair regrowth and saw visible improvement around the 4th or 5th month.

A 24-year-old tried minoxidil, finasteride, keto shampoo, and derma-rolling for hair loss but saw no improvement and is now at Norwood 5. They feel there's nothing more they can do and are considering going bald despite not liking the look.

A user shared their 3-month progress using 1mg oral finasteride daily and 5% topical minoxidil twice daily, along with Pura D’Or anti-thinning shampoo and a scalp massager. They noticed initial worsening but later saw hair follicle recovery.

A user shared their 2-month progress using finasteride (1mg) daily, topical minoxidil (5%) daily, and dermarolling twice a week, noting some regrowth and satisfaction with the results. Another user complimented the progress, and the original poster detailed their dermarolling routine.

A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

A user has had great results with a spray containing 6% minoxidil, 0.03% finasteride, and 0.25% tretinoin from Roman but is seeking cheaper alternatives with the same ingredients. They are looking for suggestions for more affordable sites or pharmacies.

A user shared their hair regrowth journey, using minoxidil, finasteride, pumpkin seed oil, dermarolling, and scalp massages. They experienced side effects but saw significant improvement in their hairline.

User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

The post discusses whether a topical serum with 0.3% finasteride, 6% minoxidil, and essential oils is as effective as a spray with the same concentrations but different ingredients for scalp absorption. The user is seeking advice on which formulation absorbs better into the scalp.

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

User shared progress pictures showing significant hair regrowth using a compounded solution of Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Latanoprost 0.005%. They reported no side effects and are satisfied with the results.

A user shared their 5-month experience using topical finasteride for hair loss, noting side effects like watery semen and puffy nipples, which led them to stop the treatment. They saw no significant hair improvement and have since switched to using minoxidil.

The user has been using finasteride and minoxidil for over 7 years, switched to dutasteride 3 years ago, and is satisfied with the results. They experienced no noticeable side effects and use minoxidil on their hairline and temples.

A female user is using a 5% RU58841 solution with 5 sprays daily and is concerned about potential reactions and the impact of wearing a bonnet. A male user mentioned using 1ml of the same solution daily via dropper.

The user experienced hair thinning, possibly due to long COVID and prediabetes, and saw regrowth after dietary changes and using biotin shampoo. They are taking vitamins and noticed significant hair regrowth, especially at the widow's peak.

A user is treating hair loss with daily 0.5mg Dutasteride, 5mg oral Minoxidil, topical Minoxidil and Dutasteride, 520mg Saw Palmetto, 5mg Biotin, and 0.8mg Folic Acid. They plan to start weekly micro-needling and mix Minoxidil with Tretinoin.

A 22-year-old male shared his one-year progress using finasteride for hair loss, showing significant improvement after 4-6 months. He experienced initial shedding but saw regrowth starting around the 4-month mark.

Results for Amplifica's AMP-303 hair loss treatment study are expected late summer 2024. The study, fully enrolled in Q1 2024, focuses on safety and tolerability.