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      community The final nail in the coffin. PP405 is confirmed JXL069.

       440 upvotes 1 month ago
      PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.

      community Has anyone tried CB-01-03 aka Clascoterone?

       2 upvotes 6 months ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Doubtful of RU58441's negative effects

      in Research/Science  2 upvotes 1 year ago
      RU58841's potential side effects, particularly heart palpitations, are debated, with some attributing them to contamination with minoxidil. Users report mixed experiences, with some seeing no side effects and others cautioning about the lack of reliable data on RU58841's safety.

      community Custom topical from Rootsbyga.

      in Treatment  4 upvotes 1 year ago
      A user received a custom topical treatment for hair loss from Rootsbyga, which includes minoxidil and possibly other ingredients to enhance its effectiveness. The initial test cost $120, and the monthly topical costs around $70, with concerns about long-term use of steroids like hydrocortisone.

      community European release of clascoterone

       13 upvotes 4 months ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community RU/Pyrilutamide access and purchase

       3 upvotes 8 months ago
      The conversation is about accessing and purchasing RU58841 or Pyrilutamide for hair loss treatment, with mentions of alternatives like Breezula. Users discuss price differences in various countries and suggest websites like rudirect.com for purchasing.

      community This past week has been horrible

       5 upvotes 9 years ago
      A 23-year-old male is worried about potential hair loss and is considering finasteride but is concerned about side effects. He received reassurance from a doctor that he might not be balding and plans to confirm with a specialist.

      community BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside)

      in Satire 1 year ago
      A satirical post where someone claims to have developed a radioactive isotope scalp serum using Polonium-210 that outperforms Minoxidil and finasteride for hair regrowth. The serum reportedly stimulates DNA repair in hair follicles, leading to significant hair density increase, but the post is met with skepticism and concerns about safety.

      community I think Ru58841 stopped my itching.

      in Chat  4 upvotes 1 year ago
      RU58841 stopped scalp itching for the user, providing relief from persistent itchiness associated with hair loss. Some users reported side effects like chest pain, while others found relief with different treatments like mometasone.

      community Apparently you can try PP405 right now!?

       30 upvotes 1 year ago
      PP405 is likely a scam, with concerns about its legitimacy and safety, as it may cause unintended tissue growth. Users suggest sticking to known treatments like finasteride and minoxidil.

      community Which dermaroller do y'all use?

      in Microneedling  26 upvotes 2 years ago
      The conversation is about recommendations for microneedling tools for hair loss, with users suggesting a dermastamp from Koi Beauty and the Derminator 2 with 12-needle cartridges.

      community Ru58841 + topical minoxidil + microneedling succes story

       339 upvotes 1 year ago
      A user shared their successful hair loss treatment using RU58841, topical minoxidil, and microneedling, noting significant improvement over three months. They chose RU58841 over finasteride due to personal preference and reported no side effects, while others discussed their experiences with different treatments and supplements.

      community Question for Russians in this subreddit

      in Product  1 upvotes 2 years ago
      The user plans to switch to oral finasteride and oral minoxidil due to insufficient results from PRP, topical minoxidil, and mild DHT inhibitors. They seek advice on purchasing these medications from My.India, questioning its trustworthiness.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

       8 upvotes 1 year ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 1 year ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

      community It's so over. Im beyond cooked

      in Update 10 months ago
      The user is experiencing hair loss despite using Dutasteride and plans to try RU58841, considering adding Oral Minoxidil. They express frustration with diffuse thinning and seek advice on managing hair loss.

      community Has anyone had suicidal thoughts because of their ruined appearance?

       4 upvotes 7 years ago
      The conversation discusses feelings of despair and low self-worth due to hair loss and other perceived physical shortcomings. The user expresses a lack of motivation and struggles with societal expectations, despite trying various self-improvement methods.

      community a hair cream that claims to reverse hairloss. need ur opinion guys

       1 upvotes 4 years ago
      A user is skeptical about a "miracle hair cream" claiming to reverse hair loss and seeks opinions on its effectiveness. They are already using finasteride, minoxidil, and dermastamping weekly but want additional help for temple hair growth.

      community Injured temple with derma rolling

      in Microneedling  2 upvotes 2 years ago
      OP injured their temple using derma rolling and tretinoin, causing peeling and potential hair follicle damage. Users suggest the injury might be permanent, possibly resulting in scar tissue where hair won't grow.

      community Verteporfin Phase 1 Human Clinical Trial In The Works - Research

       92 upvotes 1 year ago
      Verteporfin is being discussed for its potential to regrow hair and heal scars, possibly aiding hair transplants or replacing them. Some users are skeptical about its effectiveness, while others suggest combining it with microneedling for better results.

      community Desperate for help - Dread shed since 5 months!

       1 upvotes 1 year ago
      The user is experiencing severe hair loss after starting Minoxidil 5% and is seeking advice, as their hair loss worsened following a second COVID infection. Despite normal hormone and vitamin levels, the user is considering additional treatments like Ketoconazole shampoo, massages, and low-level laser therapy.

      community Does anyone here use MVSupplements.con products?

       1 upvotes 11 months ago
      The conversation discusses concerns about MVSupplements.com products, specifically the Min+Ru spray and GHK Serum, due to discrepancies in ingredient lists and recent poor feedback. Users also mention a price increase and one user reports no issues with the RU powder.

      community Questions regarding starting Dermarolling, Rogaine foam, retinal/retinol

       4 upvotes 7 months ago
      The conversation discusses using Rogaine (minoxidil foam) for hair loss, with questions about enhancing its effectiveness with tretinoin or retinol and incorporating dermarolling. The user has been using finasteride for 7 years and is considering starting minoxidil despite concerns about shedding.

      community Is RU58841 worth it? Has anybody seen success on it?

      in Technology  6 upvotes 6 months ago
      RU58841 is used by some for hair loss, with mixed results; one user reported success with no side effects, while another experienced lung and heart issues. RU58841 is often sourced from third-party vendors and used alongside treatments like dutasteride and minoxidil.