Actifollic selling Pyrilutamide as a treatment for hair loss, with people debating its efficacy compared to Minoxidil and Finasteride in combination with RU58841.
A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.
The relative strength of Pyrilutamide compared to RU58841 in terms of androgen receptor binding affinity. It has been noted that Pyrilutamide is 4x stronger than RU58841, with a higher binding affinity than DHT itself.
Hair loss treatments, including the use of Minoxidil and Finasteride, with a user sharing their 8-month update on progress made. Others have chimed in to provide encouragement and advice for continued treatment.
The post and conversation are about a hair loss treatment regimen involving 30% minoxidil cream nightly, 5% minoxidil in the mornings, finasteride, weekly 1.5 derma pen, daily 0.5 microneedling for minoxidil absorption, daily multivitamin with biotin, low-level laser therapy every other day, daily scalp massages, Hims shampoo, and daily coffee rinses. The user hopes for hair regrowth and plans to update in one year.
Alpecin Caffeine shampoo is ineffective for stopping hair loss, with unreliable supporting research. Finasteride is effective in reducing hair loss by lowering DHT levels.
Young guys with thick hair asking if they're going bald and people discussing early action for hair loss treatments like Minoxidil and Finasteride. Some users share their positive experiences with these treatments.
The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.
Biotin supplements are not effective for hair loss unless you are actually deficient, which is rare. Some users report improved hair quality with biotin, but there's no evidence supporting its use for hair loss in healthy individuals.
User experienced significant hair growth in 3 months using finasteride, minoxidil, microneedling, and scalp massages. Others questioned the authenticity of the results due to the rapid progress.
The conversation is about a user trying topical melatonin mixed with minoxidil to reduce hair shedding after not seeing desired results with finasteride and minoxidil alone. Another user suggests that instead of daily updates, the original poster should share their results after a few weeks.
User shares 3.5-month hair transformation using 0.5 mg Dutasteride daily and Minoxidil 2x daily. Others express amazement and discuss safety profiles of treatments.
Minoxidil may cause skin aging effects like wrinkles and dark circles, but evidence is mixed. Alternatives like dermarolling and retinol are suggested.
The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.
User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.
User asked dermatologist for finasteride, received latanoprost and diprogenta cream instead. Others suggest latanoprost is expensive and not better than minoxidil, recommend trying another doctor for finasteride.
A person considering finasteride for hair loss checked their hormone levels before starting treatment. They are concerned about the potential increase in estradiol and its effects, as well as the impact on their sex hormone-binding globulin (SHBG) and free testosterone levels.
The conversation is about a person's one-year progress using finasteride and minoxidil for hair loss, with intermittent use of RU58841, showing improved hair quality, density, and thickness without side effects. Users complimented the improved appearance and suggested the longer hair also enhanced their look.
The conversation discusses the high prices of hair loss treatments, specifically cb-03-01 and KY19382. It also mentions the use of Minoxidil, finasteride, and RU58841.
Chinese company gets green light for Pyrilutamide Phase II trial for androgenetic alopecia. Androgen receptors downregulate in androgen deficient environments.
User reports 3-month progress using Fin 0.5mg/day, 1x minox 5%, keto shampoo every 3 days, and microneedling 1.5mm a week. Others suggest shaving sides or trying shaved head look, while some discuss side effects and dosages.
A user likes a natural hair styling product that makes their hair look thicker and is seeking opinions on whether it could harm hair follicles. They also question if cold water is sufficient to wash the product out and mention they are experiencing hair thinning.
User shares progress update on hair loss treatment using finasteride, minoxidil, and microneedling. Others congratulate and ask questions about treatment details, such as microneedling tool, needle size, and side effects.
A user was frustrated with delays in getting finasteride for hair loss, was prescribed minoxidil, and found a vitamin B7 deficiency. They are questioning if the deficiency could cause receded temples and considering finding a new dermatologist.
Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.
The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a study suggesting that sulforaphane may reduce DHT levels and promote hair growth in mice.
The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.