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Adding topical spironolactone to a finasteride regimen for hair loss. Users discuss different mechanisms and suggest also using minoxidil.

The user experienced side effects from daily 1 mg Finasteride and switched to 0.5 mg every other day, supplemented with creatine, tongkat ali, tribulus terrestris, vitamin D3, bromantane, l-tyrosine, and caffeine. They also use weekly 1.5 mm microneedling and daily 50 mg RU58841, except on microneedling days, to manage hair loss.

Using Tretinoin every other day with daily Minoxidil may help with hair regrowth, and some users find it more effective than daily use. There are concerns about irritation and absorption, but small amounts seem to minimize harm.

RU58841 is being discussed as a hair loss treatment without using finasteride or dutasteride. Users are sharing their experiences and success with RU58841 alone.

The conversation discusses the duration of hair shedding caused by RU58841. The user is stressed and seeking information on how long the shedding phase lasts.

The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.

VDPHL01, an extended-release oral minoxidil tablet, showed promising results in improving hair coverage for 79 to 86% of men in a trial, with fewer side effects compared to standard doses. Many users prefer oral minoxidil over topical due to ease of use and fewer side effects, especially for those with pets.

The user experienced significant hair regrowth using oral finasteride (1 mg) and oral minoxidil (2.5 mg) daily, with minimal side effects. They also use testosterone to balance any libido effects from finasteride.

A user with slight hair thinning is seeking alternatives to minoxidil due to concerns about heart rate effects, despite using finasteride without issues. They are looking for options that don't affect the heart.

Apply minoxidil at least 1-2 hours before bed to ensure it dries and doesn't transfer to the pillow. Foam dries faster than liquid, and using a satin beanie after drying can help prevent transfer.

Finasteride prescriptions can be transferred to Costco for cheaper prices, and Costco does not require a membership for pharmacy purchases. Users discuss various options for obtaining finasteride and minoxidil, including splitting 5mg tablets for cost savings and using different pharmacies for better deals.

Morr F Aqua, an alcohol-free Minoxidil, is discussed for its absorption effectiveness. Users also mention using finasteride and RU58841 for hair loss treatment.

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

The user has been using finasteride for two years, gradually increasing the dose to 1 mg, and is satisfied with the results despite not using minoxidil due to lifestyle constraints. Another user shared their experience with finasteride, noting side effects like discomfort and loss of libido, and ultimately stopped using it before planning to have a child.

Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

Adding melatonin to minoxidil can improve hair growth and thickness, and it's easy to use with minimal side effects. The recommended concentration for melatonin in the solution is between 0.05% and 0.2%.

RU58841 is discussed as a hair loss treatment, with users considering lower doses like 2.5% to reduce costs. Some users suggest that if already blocking DHT, lower doses might still be effective unless there's high sensitivity to DHT.

The user stopped using finasteride due to side effects and is considering Fluridil (Eucapil) as an alternative for hair loss treatment. They are exploring other options like RU58841 and are interested in the experiences of others with Fluridil, noting its good safety profile despite the cost.

Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

Breezula (clascoterone) is expected to be available by late 2026, showing good long-term results with minimal side effects. KX-826 (pyrilutamide) acts faster but is still in earlier development stages.

Breezula's phase 2 showed reduced efficacy after 6 months, but phase 3 had positive results, causing confusion about any changes made to the drug. There is frustration over the long timeline for hair loss treatments, with some users expressing more interest in other potential treatments like GT-20029.

Creating a liposomal gel with Pyrilutamide for hair loss to reduce systemic effects, similar to Xyon's gel. The discussion includes concerns about ingredient sourcing and the benefits of targeted topical treatments.

A user is using Minoxidil, finasteride, saw palmetto, and Minimalist RCP serum to address hair thinning, with some success but concerns about the long-term benefits of Minimalist. They plan to continue Minoxidil and finasteride for another year before considering a hair transplant.

Revivhair serum is discussed as a potential treatment for mild hair thinning, but skepticism exists about its effectiveness without proven treatments like finasteride, dutasteride, or minoxidil. Users share experiences with various treatments, noting side effects and exploring alternatives like topical dutasteride and alfatradiol.

A user developed a rash after 3 years of using Kirkland minoxidil foam, possibly due to a change in ingredients. They are considering switching to Foligain or Rogaine foam to avoid further issues.

The conversation discusses hair loss treatments, specifically Verteporfin. Users also mention Minoxidil, finasteride, and RU58841.

The user is experiencing hair regrowth using 1.2 mg oral finasteride and 3 mg oral minoxidil after aggressive balding. They express concerns about hair loss affecting confidence and consider additional treatments like dutasteride.

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.

The user started shedding hair after beginning testosterone replacement therapy (TRT) despite using dutasteride and minoxidil, and added RU58841 to address the shedding. They reduced their TRT dose and hope RU58841 will stop the shedding quickly.