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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 4 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Oxytocin, empathy, hair, and cinnamon

      in General  138 upvotes 5 months ago
      Low oxytocin levels in hair are linked to reduced empathy and may affect hair growth. Cinnamic acid can promote hair growth by activating oxytocin receptors.

      community 50% test increase after 18 months of taking DUT

      in Update  57 upvotes 5 months ago
      A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.

      community 11 months of 1.5 mg Finasteride with blood samples

      in Finasteride/Dutasteride  292 upvotes 7 months ago
      A user took 1.5 mg Finasteride and topical Minoxidil for 11 months, resulting in significant changes in blood values but no noticeable hair improvement. They experienced side effects like mood swings and increased visceral fat, leading them to stop Finasteride.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  101 upvotes 10 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Is GT20029 supposed to regrow hair as well?

      in Treatment  10 upvotes 1 year ago
      The user is considering switching from finasteride to dutasteride for hair loss. They are unsure if GT20029 can regrow hair, particularly on the temples. Another user mentions that regrowth on finasteride can take up to 2 years.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  7 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community Kintor KX-826 Group Buy Feedback

      in Research/Science  27 upvotes 2 years ago
      The conversation is about a group of people trying KX-826 for hair loss, with no serious side effects reported after 25 days of use. Some participants are experiencing less scalp itch and shedding, but it's too early for definitive results.

      community Been on Min and Fin for Years and I am Devastated.

      in Treatment  64 upvotes 2 years ago
      Guyman567 has been using oral finasteride and topical minoxidil for years but continues to experience hair loss and thinning, which has affected his confidence. He has tried various treatments including topical finasteride, microneedling, and vitamins, and is considering a hair transplant but is concerned about ongoing hair loss.

      community Here is my hair regrowth plan

      in Treatment  4 upvotes 4 years ago
      The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  209 upvotes 3 months ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Little Update - Min 6 Months and Fin 5 Months

      in Progress Pictures  261 upvotes 9 months ago
      The user shared a 6-month progress update on hair regrowth using Minoxidil and 5 months of Finasteride, along with a hair transplant of 4,200 grafts. Commenters reacted positively, discussing the effectiveness of these treatments and the impact on self-image.

      community Finasteride vs Dutasteride: The Science

      in Research/Science  169 upvotes 1 year ago
      The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.