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      community Which retinoid for better min absorption?

      in Product  4 upvotes 2 months ago
      User is on vacation in Greece and wants to buy tretinoin or isotretinoin to improve Minoxidil absorption. They are considering isotretinoin since it is available over-the-counter in Greece but requires a prescription back home.

      community I'm looking for treatment non-responders

      in Chat  7 upvotes 2 months ago
      The user has been using oral minoxidil, dutasteride, and RU58841 but continues to experience hair loss. They seek advice on why the treatments aren't working and if others have had similar experiences.

      community Cetirizine (Zyrtec), to help with inflammation.

      in Product  3 upvotes 2 months ago
      The user experiences an itchy scalp and finds relief using shampoo and Zyrtec, which helps with inflammation. They are unsure if the issue is related to histamines or seborrheic dermatitis.

      community How do you guys apply topicals every single day?

      in Minoxidil  1 upvotes 2 months ago
      The user is struggling with the daily application of topical treatments like Minoxidil and melatonin for hair loss, concerned about the impact on hair cleanliness and texture. They are unsure how to manage the routine without washing their hair daily, which dries it out.

      community Fin was behind Michael Scott's glowup

      in Satire  410 upvotes 2 months ago
      Michael Scott's hair improvement was likely due to a hair transplant and possibly finasteride. Some believe his hair was intentionally styled poorly in the first season.

      community Adding cetirizine tablet to minoxidil

      in Treatment  3 upvotes 2 months ago
      A user wants to add cetirizine tablets to their minoxidil bottle and asks how many 10mg tablets to crush for a 100ml bottle. They seek advice on the correct dosage.

      community antihistamine for scalp inflammation??

      in Chat  6 upvotes 2 months ago
      Cetirizine 10mg daily reduced hair shedding by 50% and lessened scalp itchiness. The user is considering long-term use for scalp inflammation and hair loss.

      community My boy Saul Goodman was on Minoxidil tabs too

      in Satire  1881 upvotes 2 months ago
      Saul Goodman was humorously depicted using high doses of minoxidil, finasteride, and spironolactone for hair loss. The conversation jokes about the unrealistic dosages and their potential side effects.

      community Tristan Tate stopped using fin i guess???

      in Satire  468 upvotes 2 months ago
      Tristan Tate's hair loss is discussed, with mentions of finasteride, minoxidil, and dutasteride as treatments. Users speculate on his hair styling, steroid use, and legal troubles.

      community 5.5 months on oral min questions. Please help😭

      in Treatment  11 upvotes 2 months ago
      The user has been on finasteride for over a year and switched from topical to oral minoxidil five months ago, but is unsure if the current shedding and small hairs are signs of improvement or worsening. They are seeking advice on whether to wait longer or switch treatments.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 3 months fin/min progress (age 31)

      in Progress Pictures  168 upvotes 2 months ago
      A user shared their 3-month progress using 1mg oral finasteride daily and 5% topical minoxidil twice daily, along with Pura D’Or anti-thinning shampoo and a scalp massager. They noticed initial worsening but later saw hair follicle recovery.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 2 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Added Tretinoin to my my routine and am shedding like crazy.

      in Treatment  1 upvotes 2 months ago
      The user has been using finasteride and minoxidil for almost 2 years with maintenance but no significant regrowth. After adding tretinoin 2 weeks ago, they experienced increased shedding and are seeking advice on whether this is a positive sign.

      community Fin/Dut shed + other questions

      in Treatment  1 upvotes 2 months ago
      The user is preparing for potential future hair loss treatments and currently uses topical minoxidil, derma rolling, and ketoconazole shampoo. They are concerned about shedding, side effects, and the possibility of starting finasteride or dutasteride along with testosterone.

      community 16M topical min Kirkland 5% 2*1 ml ED, saved from dead

      in Progress Pictures  45 upvotes 2 months ago
      A user shared their hair loss journey, detailing their use of Kirkland Minoxidil 5%, finasteride, dutasteride, and weekly dermarolling. They experienced initial success with minoxidil but faced setbacks with oral minoxidil and are now back on topical treatments.

      community Minoxidil + Fin 1 mg + Dermaroller 1x week - 1 year results

      in Is this regrowth?  105 upvotes 2 months ago
      A user used Minoxidil twice daily, 1 mg finasteride in the morning, and a dermaroller weekly for a year but is unhappy with the results and sperm quality. Others suggest continuing the regimen, noting hair maintenance and thickness, and considering additional treatments like dutasteride or a hair transplant.

      community My first pill of Dutasteride is today

      in Finasteride/Dutasteride  26 upvotes 2 months ago
      A user started taking Dutasteride and experienced significant shedding initially, but it has since stopped after three months. They noticed some changes but are unsure if they are solely due to Dutasteride.

      community 16M Ketoconazol 2% and redensyl

      in Is this regrowth?  1 upvotes 2 months ago
      A 16-year-old started using ketoconazole 2% and redensyl for hair loss, as minoxidil and finasteride are not recommended until age 18. They are seeking feedback on whether the treatment is effective or maintaining their hair.

      community Minoxidil For 2 Years, What is this?

      in Treatment  111 upvotes 2 months ago
      The user has experienced significant hair thinning despite using 2.5 mg minoxidil for 2 years. Other users suggest adding finasteride or dutasteride and consulting a dermatologist for a proper diagnosis.

      community My doctor lowered my Minoxidil from 5mg to 2.5mg

      in Minoxidil  71 upvotes 2 months ago
      A user discussed their doctor lowering their Minoxidil dose from 5mg to 2.5mg, expressing concerns about losing hair gains. Other users suggested that 2.5mg is safer long-term and speculated the doctor is being cautious about side effects.