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      community Topical rapamycin, metformin, a-kg grow hair

       13 upvotes 6 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community The Efficacy of Topical Rapamycin for Hair Regrowth

       6 upvotes 3 years ago
      The conversation discusses the effectiveness of topical Rapamycin for hair regrowth and color restoration. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Self-Experiment - Topical Rapamycin or a-KB

       4 upvotes 4 years ago
      A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

      community Almost 4 months progress on finasteride and minoxidil

      in Progress Pictures  38 upvotes 1 month ago
      The user shared their positive progress using finasteride and minoxidil for hair loss, experiencing no side effects except longer eyelashes and a thicker beard. They expressed gratitude for community support and mentioned both medications are taken orally, with finasteride being a Mexican generic brand.

      community RT1640 - Gray Hair Reversal Recipe

       3 upvotes 4 years ago
      The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

      community My report taking dutasteride 0.5 and oral minoxidil 2.5 for 70 days

      in Update  7 upvotes 1 month ago
      The user reported initial shedding but noticed darkening and thickening of hair at the temples after 70 days of using dutasteride 0.5 mg and oral minoxidil 2.5 mg. Others shared similar experiences and advised patience, as early shedding is common and improvement may take 6 to 12 months.

      community What happened with verteporfin?

       30 upvotes 1 month ago
      Verteporfin, combined with microneedling, shows promise for hair regrowth by allowing hair follicles to grow in wounds, but it's expensive and painful. Pai-1 inhibitors may also help prevent hair loss by degrading fibrosis, and some users continue using minoxidil alongside these treatments.

      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Topical finasteride in Europe?

       4 upvotes 3 years ago
      The conversation discusses using topical finasteride as an alternative to oral medication for hair loss, with mentions of minoxidil, microneedling, ketoconazole shampoo, and other treatments. A user shares their experience with topical finasteride and other treatments, noting improved hair density.

      community Is there any new drug that looks promising ?

       26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community 25 years on Finasteride and it's not working anymore.

       324 upvotes 6 months ago
      A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT.

      community Been on min+fin for 2 years, only gotten worse. B/A pics included

      in Chat  88 upvotes 7 months ago
      The user experienced worsening hair loss despite using finasteride and topical minoxidil for two years and is considering oral minoxidil and dutasteride. Suggestions include microneedling, stress management, and alternative treatments like topical finasteride or ketoconazole shampoo.

      community 3,5 months of only topical minoxidil

       776 upvotes 9 months ago
      A 24-year-old reported new hair growth on temples after 3.5 months of using topical minoxidil without shedding. They plan to add finasteride to maintain progress, as minoxidil alone may not be enough long-term.

      community Did George Clooney did a hair transplant?

       2609 upvotes 10 months ago
      George Clooney likely had a hair transplant, as many Hollywood actors do to maintain their appearance. Treatments like finasteride and hair transplants are common among celebrities to combat hair loss.

      community Bruteforcing alopecia or the new advent of science progress

       22 upvotes 1 year ago
      Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

      community 1 year on fin. No results. I give up.

      in Finasteride/Dutasteride  43 upvotes 3 years ago
      A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

       737 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community 10 Days Post-Op: Hair Transplant Results and Experience

       508 upvotes 2 years ago
      A user shared their positive experience with a hair transplant at Dr. Resul Yaman Hair Clinic in Istanbul, including before and after photos. They are considering taking oral Minoxidil post-operation but are avoiding Finasteride due to side effects.