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      community Shoutout to Zinc pyrithione and Piroctone olamine

       3 upvotes 1 year ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community PP405 could be released before GTA 6

      in Chat  133 upvotes 9 months ago
      PP405 is discussed as a potential hair loss treatment, but its effectiveness and safety are uncertain. Some users express skepticism, while others are hopeful, comparing it to existing treatments like Minoxidil and Finasteride.

      community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

       211 upvotes 1 year ago
      PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

      community The (many) benefits of buzzing during treatment

      in Chat  28 upvotes 1 year ago
      Buzzing hair can improve mental health and make applying treatments like Minoxidil and microneedling easier. It helps with self-acceptance and reduces the impact of hair loss on appearance.

      community Won’t pp405 and gt20029 be patented and be almost unreasonably expensive

       29 upvotes 1 year ago
      Concerns about the potential high cost of new hair loss treatments, pp405 and gt20029, were discussed, with some users willing to pay a premium if they are effective. Alternatives like finasteride and minoxidil are mentioned as current, more affordable options, and there is speculation about future generic versions and black market availability.

      community Different Topical Dutasteride Formulations

       3 upvotes 3 years ago
      The conversation discusses the best vehicle for topical dutasteride, comparing Trichosol, Transcutol, and a gel version. It also mentions using Transcutol with ethanol to enhance transdermal delivery of Bimatoprost.

      community 8 months progress Before/After

      in Is this regrowth?  553 upvotes 1 year ago
      The user is pleased with their hair transplant results but is concerned about the vertex area. They use Minoxidil and finasteride daily and had the procedure at a clinic in Athens.

      community 16 month update post hair transplant and meds

       43 upvotes 10 months ago
      The user is generally happy with their hair transplant results but has concerns about graft density and placement, particularly on the left temple and hairline. They are using finasteride and minoxidil inconsistently, plan to add Priorin, and are considering microneedling and PRP sessions for future care.

      community Rational Review of Pelage Results

      in Chat  11 upvotes 1 year ago
      A treatment showed a 20% hair density increase in weeks, with nearly a third of participants experiencing significant results, while questions remain about its long-term efficacy and effectiveness across different scalp areas. There is interest in combining it with finasteride and minoxidil for potentially better outcomes.

      community Update from December's Pyrilutamide GB?

       13 upvotes 4 years ago
      Participants discussed hair loss treatments, specifically Pyrilutamide, with some experiencing side effects like heart palpitations and anxiety. There is uncertainty about the drug's effectiveness, and a new group buy is planned with a different lab due to concerns about purity.

      community Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results

       371 upvotes 8 months ago
      Clascoterone 5% solution shows strong potential for hair growth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.

      community Am I missing something with pp405?

       34 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community Getting PP405. Now…. or as soon as possible

       147 upvotes 1 year ago
      People are discussing obtaining and testing PP405 for hair loss treatment, with concerns about its purity and effectiveness. Some are considering delaying hair transplants, while others suggest using existing treatments like finasteride and minoxidil.

      community formula 82D for diffuse androgenic alopecia (DUPA)

       15 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community Phase 3 for PP405 will now start in 2027

      in Chat  81 upvotes 1 month ago
      Phase 3 for PP405 will start in 2027, disappointing many who expected it this year. Some users are trying treatments like topical minoxidil and topical dutasteride while waiting for new developments.

      community topical exosomes - experimenting

       1 upvotes 6 months ago
      The conversation is about experimenting with topical exosomes for hair loss treatment, alongside microneedling, Happy Head's gel-like topical, and Ordinary's hair serum. The user also mentions the availability of treatments like latanoprost and Redensyl.

      community Can one of you smarty pants explain the PP405 results? Why did they choose to highlight that 31% had 20% increase in density? What about the other 69%? What about other ±% in density? Why is this considered a great result? Thanks.

       13 upvotes 10 months ago
      PP405 shows promise in reactivating dormant hair follicles, with 31% of users experiencing a 20% increase in hair density in a short period. It may work faster than minoxidil and without side effects, but its long-term effectiveness is still uncertain.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 3 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Budget LLLT Options: Are the under $200 products legit?

      in Technology  8 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically the effectiveness and legitimacy of low-level laser therapy (LLLT) devices under $200. The user has seen positive results with finasteride, minoxidil, ketoconazole, microneedling, and scalp massages, and seeks advice on affordable LLLT options.

      community PP405: latest news. Really interesting

       29 upvotes 5 months ago
      The conversation discusses impressive results from a 28-day application of a hair loss treatment. Users compare it to their experiences with Minoxidil and Dutasteride, noting excitement over the new findings.

      community 7 Month hair transplant update (3153 grafts, HLC)

       28 upvotes 5 days ago
      A user shared a 7-month update after receiving 3,153 grafts in a hair transplant, noting ongoing growth but some areas still appear sparse and red. They are in contact with the clinic for feedback and are hopeful for further improvement.

      community ”Why are we not funding this?” - Peter Griffin

       221 upvotes 1 year ago
      Topical finasteride can reduce scalp DHT as effectively as oral finasteride with fewer systemic effects, but availability is limited. Some users make their own solutions due to limited access.

      community clascoterone powder to topical diy

       4 upvotes 4 months ago
      The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.