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      community Maxogen-X progress log

       4 upvotes 5 years ago
      The user tried various hair loss treatments, including Maxogen-X, Dualgen15, minoxidil, finasteride, and dermarolling, but experienced limited regrowth and some side effects. They eventually switched to oral minoxidil, hoping for better results.

      community Thoughts on Lactobacillus Reuteri 6475?

       4 upvotes 1 year ago
      Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 1 year ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Is RU58841 safe or is pyrilutamide better option

       7 upvotes 1 month ago
      RU58841 and pyrilutamide are discussed as alternatives to 5AR blockers for hair loss, with mixed opinions on their safety and effectiveness. Some users report positive experiences with RU58841, while others express concerns about its safety.

      community Increased shedding with black bulbs after restarting minoxidil

       4 upvotes 2 weeks ago
      An 18-year-old restarted using topical minoxidil consistently after noticing diffuse thinning and is experiencing increased shedding with black bulbs. Users suggest that shedding is common and may stop with consistent use, but the black bulbs could indicate a strong response to minoxidil.

      community Will PP405 render Minox and Fin obsolete?

       30 upvotes 1 year ago
      PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.

      community Does the PG-free version of RU58841 have lower absorption compared to the PG version?

       6 upvotes 11 months ago
      The conversation discusses the absorption and effectiveness of PG-free versus PG versions of RU58841, with some users believing PG improves efficacy while others see no difference. Concerns about RU58841's potential side effects on the endocrine system are also mentioned, with one user considering switching to pyrilutamide.

      community The lowest cyproterone dose to stop mpb

       4 upvotes 3 years ago
      The conversation discusses using cyproterone acetate at 12.5 mg to manage hair loss, with concerns about its effects on testosterone and potential health issues. Other treatments mentioned include finasteride, dutasteride, minoxidil, and RU58841, with varying experiences and outcomes.

      community Guys I actually can’t believe pyrilutamide is actually working!!

       29 upvotes 4 months ago
      Hair regrowth was achieved using minoxidil, nizoral, alfatrodial, and pyrilutamide after finasteride caused side effects. The user recommends this combination for those who can't tolerate 5AR inhibitors, stressing consistent use.

      community Are there any reviews of KX-826 yet?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide (KX-826) is being discussed as a potential hair loss treatment, with some users reporting no regrowth after three months. It may prevent further hair loss but might not promote regrowth unless combined with Minoxidil.

      community Any long term users of pyrilutamide here?

      in Research/Science  5 upvotes 5 months ago
      The conversation is about using pyrilutamide for hair loss, with the original poster also using minoxidil and nizoral for maintenance. The poster experienced side effects from finasteride and is seeking feedback from long-term pyrilutamide users.

      community Oral Minoxidil - The Hyper-Responder Concept

       4 upvotes 10 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Anyone having success with pyrilutamide?

       5 upvotes 1 month ago
      Pyrilutamide is being discussed for hair loss treatment, with one user reporting no success after six months and another using it alongside finasteride for two months. The conversation seeks recommendations and experiences with pyrilutamide.

      community (24M) 5 months on minxidil and fin

      in Progress Pictures  7 upvotes 1 year ago
      A 24-year-old male shares his 5-month progress using 1mg finasteride daily, biotin supplements, multivitamins, 3ml minoxidil daily, and derma rolling twice a week. A user inquires about hair shedding and the type of minoxidil used.

      community Is PP405 really that good or another "scam"?

       3 upvotes 7 months ago
      PP405 is considered a potential alternative to minoxidil and finasteride, but its effectiveness and safety are still uncertain. Many users suggest sticking with proven treatments like finasteride and minoxidil due to the lack of long-term data on PP405.

      community Have to stop min after 3 years, diagnosed with heart murmur

       5 upvotes 5 months ago
      The user must stop minoxidil due to a heart murmur and is considering alternatives like nanoxidil or stemoxydine while continuing dutasteride. Suggestions include adding pyrilutamide and alfatradiol or switching to topical minoxidil at a lower concentration.

      community Miniaturization(?) after 12 months on oral fin/min compound

       13 upvotes 1 month ago
      After 12 months on an oral compound of finasteride, minoxidil, and biotin, the user experienced a seasonal shed and noticed thinner hairs at the hairline, raising concerns about ongoing miniaturization. Another user shared a similar experience and mentioned switching to dutasteride after genetic testing showed finasteride was ineffective.

      community Pyrilutamide vs topical finasteride

       2 upvotes 1 year ago
      The user is considering switching to topical finasteride or pyrilutamide to stabilize hair loss before a hair transplant, currently using oral minoxidil and finasteride. Suggestions include sticking to the current regimen as it is already potent, and caution against using pyrilutamide from unreliable sources.

      community Loniten 2.5mg on backorder in Toronto.

       7 upvotes 3 days ago
      Loniten 2.5mg is on backorder in Toronto, causing issues for those trying to start oral Minoxidil. Users suggest alternatives like splitting 10mg tablets or trying different brands.

      community So is this the actual trial results for pp405?????

       94 upvotes 5 months ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.