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      community Fucking hell (Easter)

      in Chat  459 upvotes 3 years ago
      User hears aunt's comment on hair loss during Easter gathering. Others discuss handling rude comments and share experiences with hair loss treatments like Minoxidil and Finasteride.

      community The most depressing things about hair loss for me

      in Chat  23 upvotes 3 years ago
      The emotional impact of hair loss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.

      community Remember to take care of your hair condition.

      in Chat  107 upvotes 3 years ago
      Taking care of hair condition through the use of shampoo, conditioner, oils and scalp scrubs, as well as advice on using Nizoral and Naturebox Olive Shampoo. Replies also included discussion about whether a bad shampoo could be causing hair loss.

      community This guy is 113 and has more hair than most people on here.

      in Satire  981 upvotes 3 years ago
      A 113 year old man who has more hair than most people, and the conversation is discussing potential genetic factors that may be responsible for this. Possible treatments such as dermarolling and minoxidil, finasteride, and RU58841 are mentioned.

      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  66 upvotes 3 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community New potential hair loss treatment (news release)

      in Treatment  186 upvotes 4 years ago
      New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  6 upvotes 4 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community 6 months fin, lots of hair lost (pics)

      in Finasteride  12 upvotes 5 years ago
      The user has been using finasteride since September 2018, dermarolling since February 2019, and applying minoxidil once a day. Despite these treatments, they have experienced significant hair loss and are unsure if they should continue.

      community My Dad seems to get his hair back?

      in Question  17 upvotes 5 years ago
      A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hair growth.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 month ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Dutasteride Literally Saves Your Hair

      in Finasteride/Dutasteride  96 upvotes 3 months ago
      Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

      community Why does it seem everyone favors finasteride over dutasteride?

      in Female  62 upvotes 5 months ago
      The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 6 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 7 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Microneedling makes a difference. Non responders, please read

      in Microneedling  66 upvotes 7 months ago
      A 48-year-old who had been thinning since 25 and reached NW4-5 baldness saw no improvement with 1mg/day finasteride and 5% minoxidil twice a day after 8 months. After copying another person's routine, they now use 0.5mg finasteride, ketoconazole shampoo weekly, daily microneedling with 0.5mm and 1mm once a week, and apply minoxidil twice daily, resulting in baby hairs on their bald spot and temples after three months.

      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 8 months ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Update: 4 Month progress on Fin/Min plus dermaroller

      in Progress Pictures  559 upvotes 9 months ago
      A user shared a 4-month update on their hair regrowth progress using finasteride, minoxidil, a dermaroller, ketoconazole shampoo, multivitamins, and biotin, and received positive reactions and inquiries from others. They also mentioned lifestyle changes such as quitting creatine, alcohol, and smoking, which may have contributed to their success.