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PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

Pelage is moving to Phase III clinical trials for PP405, a hair loss treatment, with results to be presented at a medical meeting. Users express skepticism and hope, comparing it to existing treatments like Minoxidil and finasteride, while discussing the potential for new hair growth in previously bald areas.

The user is experiencing underwhelming hair regrowth results from using oral finasteride and topical minoxidil, considering switching to dutasteride and oral minoxidil. They stopped microneedling and tretinoin, which might have affected progress.

The user used finasteride and minoxidil daily for 199 days, resulting in thicker hair and some progress in the temples. They experienced initial shedding but reported no side effects and are considering using a derma roller for further improvement.

The conversation discusses hair regrowth using 2-deoxy-d-ribose (2DDR) combined with minoxidil, with some users noting new hair growth. The original poster has been using minoxidil for 12 years and is considering combining 2DDR with finasteride, despite past side effects.

The user experienced significant hair improvement using 1mg finasteride daily without side effects. They are advised to continue treatment to maintain results and consider cost-effective purchasing options.

PP405 is criticized for overhyped claims and cherry-picked data, with doubts about its effectiveness compared to minoxidil and finasteride. Many users express skepticism, emphasizing the need for more comprehensive trial results.

The user shared progress pictures showing significant hair regrowth using Minoxidil and a dermapen, expressing concerns about potential side effects of finasteride due to low testosterone levels. Another user reported increased testosterone and no side effects from finasteride, with improved libido.

The conversation is about making homemade topical finasteride. Propylene glycol is suggested to help the solution stay on the scalp longer.

The user shared their hair regrowth journey using treatments like dutasteride, minoxidil, microneedling, tretinoin, Nizoral, silica, biotin, and hormone replacement therapy (HRT) with cyproterone and estradiol. They reported substantial hairline improvement and some crown thinning, with hopes for further progress.

A 22-year-old switched from finasteride to dutasteride for hair loss treatment, also using RU58841, and is managing hypothyroidism. Despite ongoing shedding, they report some improvement and plan to continue dutasteride for a year before considering minoxidil.

The user has been using Minoxidil, Finasteride, and HRT for hair regrowth, but is not fully satisfied with the progress after 11 months. They are considering changing treatments, including possibly switching to Dutasteride and adjusting their HRT regimen.

A 25-year-old male experienced significant hair regrowth after one year of using 0.5mg daily finasteride, with plans to add 1.25mg oral minoxidil and microneedling for further improvement. He also uses Nizoral shampoo weekly and reports no current side effects.

The user switched from Finasteride to Dutasteride 0.5mg daily for six months, experienced significant shedding, and noticed improvement after six months. They had a hair transplant last year and reported minor side effects, including a reduced sex drive.

The user is considering RU58841 and has been using dutasteride since age 17. They are seeking affordable SARD options, mentioning ASC-J9, GT20029, and AH001.

Breezula, a topical treatment, is anticipated to be available in the US by mid-2027 as a potential alternative to finasteride with fewer systemic side effects. There is ongoing debate about its effectiveness and some users report similar side effects to finasteride.

The user experienced significant hair regrowth over 8 months using finasteride, minoxidil, and a custom topical mix including progesterone, cortisone, and alpha 5 estradiol. They reported no side effects and noticed improvement around the third month.

The user is experiencing hair regrowth using 1.2 mg oral finasteride and 3 mg oral minoxidil after aggressive balding. They express concerns about hair loss affecting confidence and consider additional treatments like dutasteride.

PP405 is a new hair growth stimulant different from Minoxidil, currently in phase 2 trials. Users discuss its potential, safety concerns, and the long wait before it might be available.

New hair loss treatments, including Breezula, VDPHL01, and PP405, are nearing Phase 3 trials, offering hope for effective solutions. Current treatments like finasteride and minoxidil remain effective, but early intervention is crucial.

A 31-year-old male has been using oral finasteride (1.2mg) and minoxidil (3mg) for 9 months and is considering adding dutasteride to his regimen. Users suggest there is progress, but some recommend trying dutasteride for more aggressive treatment.

The user has been using oral finasteride and minoxidil for five months with some progress and plans to switch to dutasteride, while also considering a hair transplant for better coverage. Suggestions include adding microneedling, Nizoral shampoo, and possibly using both oral and topical treatments for improved results.

The post discusses a user's successful hair regrowth using finasteride, dutasteride, topical minoxidil, and estrogen over nine months. The user, who is male-to-female (mtf), reports significant regrowth and no side effects beyond typical hormone replacement therapy effects.

A user shared their 15-month hair regrowth progress using 1mg finasteride daily and topical minoxidil once daily, noting significant improvement after adding finasteride. They experienced mild side effects, including reduced erection strength after a year.

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

The user experienced significant hair regrowth in 4-5 months using finasteride (1 mg daily) and topical minoxidil twice a day, with initial mood side effects that normalized. The progress pictures show improved hairline, and the user noted the hair might have been slightly wet in the photos.

A 25-year-old male experienced hair loss after taking breaks from oral dutasteride and minoxidil, leading to concerns about losing progress. He is advised to remain consistent with his current regimen and avoid adding spironolactone.

A 16-year-old is experiencing hair loss and is using minoxidil, finasteride, and plans to add RU58841, while considering other treatments like MK-677 and microneedling. Concerns are raised about the potential impact of these treatments on puberty and development.

User shared progress pictures showing significant hair improvement after using finasteride (0.25-0.5mg daily) for 11 months. Other treatments like microneedling, ketoconazole, and scalp massage were mentioned but not used consistently.

Significant hair regrowth was achieved over six years using Minoxidil, Finasteride, and daily 0.25mm dermarolling. Finasteride had the most significant impact, with no reported side effects.