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      community [24 M] 8 months of progress in fighting hair loss

      in Progress Pictures  519 upvotes 5 months ago
      A 24-year-old male shared his 8-month progress in fighting hair loss using 1mg finasteride daily, 5mg minoxidil daily, 5mg biotin daily, and topical minoxidil nightly. He experienced no side effects and noted improved confidence and reduced shedding.
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      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 5 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community High Nicotine use and Hair Loss

      in Chat  86 upvotes 5 months ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

      community Oral vs Topical Finasteride for Trans Women

      in Transgender 5 months ago
      A user is using a Finoxidil topical spray and is curious if oral Finasteride would be more effective, considering they are already on a DHT blocker called Cyproterone. They are concerned about the potential impact of oral Finasteride on their transition.

      community Approximately 1 month on oral dut+ oral min

      in Progress Pictures  103 upvotes 7 months ago
      A user shared progress pictures after one month on oral dutasteride and minoxidil, noting some improvement despite initial shedding. They previously used finasteride for a year without noticeable change and emphasized the importance of photo comparisons.

      community … thoughts about current progress?

      in Is this regrowth?  7 upvotes 7 months ago
      A 30-year-old man shared his hair regrowth progress using Minoxidil and Finasteride. He experienced side effects initially but resumed treatment, and now sees improvement.

      community Where do you guys buy your stuff?

      in Product  8 upvotes 8 months ago
      The post discusses purchasing hair loss treatments like oral minoxidil and finasteride, which were found cheaply in Argentina. The user asks where others buy similar products, including topical minoxidil, finasteride, dutasteride, and RU58841.

      community Why is there so many people claiming Dutasteride destroyed their hair?

      in Chat  25 upvotes 8 months ago
      Some people claim Dutasteride worsened their hair loss, causing concern among users. Reasons suggested include initial shedding phases, incorrect attribution to Dutasteride when other factors are involved, genetic variations affecting drug response, and the possibility of non-authentic medication.

      community Had Anyone Here Actually Used More Than 0.5mg of Dut?

      in Finasteride/Dutasteride  17 upvotes 8 months ago
      A user inquires about the effectiveness of using more than the standard 0.5mg dose of Dutasteride for hair loss, mentioning studies suggest 2.5mg is more effective. Another user shares their experience of taking 1mg without noticing a difference, despite studies indicating 2.5mg may be better.

      community I’m over it. So glad to not worry about hair anymore.

      in Shaved/buzzed  569 upvotes 9 months ago
      A user shared their positive experience with shaving their head, feeling liberated from worrying about hair loss. Some discussed their own hair loss treatments, including finasteride, oral minoxidil, and Rogaine, while others expressed support for the shaved look.

      community What's the exact relation with green tea and dht?

      in Chat  9 upvotes 9 months ago
      The conversation is about the effects of green tea on DHT levels and its impact on hair loss. It concludes that natural remedies like green tea are less effective than hair loss drugs such as Minoxidil, finasteride, and RU58841.

      community Shedding about 4 years, now smth between NW3-4. Believed reasin was my low ferretin, but still has hairlost. Dht level is 425. Could it be dht that is the reason?

      in Chat  3 upvotes 9 months ago
      Loose-Message9596 has been experiencing hair loss for 3-4 years, initially due to low ferritin and vitamin D levels, and has tried treatments like vitamins, System 4, and PRP therapy. They are considering starting finasteride and minoxidil but are unsure due to their relatively low DHT level of 425.

      community General tips for frequently asked questions for you fellas

      in Treatment  7 upvotes 9 months ago
      The conversation provides advice on hair loss treatments, emphasizing the importance of following instructions for Minoxidil and Finasteride use, considering micro-needling to enhance treatment effectiveness, and incorporating hair oils, vitamins, and appropriate shampoos. The user shares their personal regimen, which includes oral Finasteride, topical Minoxidil, rosemary oil, micro-needling, supplements, and specialized hair care products, and stresses the necessity of consistency for successful results.

      community Less messy way of applying minoxidil

      in Chat  25 upvotes 9 months ago
      The conversation suggests using a dropper to apply minoxidil to the scalp without force for a less messy application compared to sprays or other methods.

      community Expectations control for SCUBE3

      in Research/Science  22 upvotes 10 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community How long have you tried topical melatonin?

      in Treatment  4 upvotes 10 months ago
      The conversation is about the effectiveness of topical melatonin for hair loss, asking for details on dosage, frequency, duration of use, results, and brand information. An update includes a skeptical view on the studies regarding melatonin's effectiveness.

      community The second shed: finasteride+minox+tretinoin

      in Progress Pictures  8 upvotes 11 months ago
      The user has been using finasteride for almost a year, starting at age 18, and added tretinoin and 5% topical minoxidil 1-2 months ago. They are concerned about hair receding again despite the treatments.

      community Finasteride 1.25mg 10 month Progress

      in Progress Pictures  148 upvotes 11 months ago
      The user shared a 10-month hair loss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.

      community Why use Finasteride instead of Dutasteride?

      in Finasteride/Dutasteride  39 upvotes 11 months ago
      People are discussing why some choose finasteride over dutasteride for hair loss, noting that while dutasteride is more effective, it's also more expensive, less researched, and potentially has more side effects. Some users shared personal experiences with side effects from both drugs, and others mentioned that finasteride is FDA approved for hair loss, while dutasteride is not, except in Japan.
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