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      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  290 upvotes 3 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community Any user of eucapil who got sides ?

      in Treatment  8 upvotes 4 years ago
      User wants to try Eucapil for hair loss but experienced side effects from finasteride. Seeks feedback on Eucapil's potential side effects.

      community I Get Side-Effects from Anti-Androgens

      in Finasteride/Dutasteride  7 upvotes 4 years ago
      Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

      community Why haven’t we seen anything about this

      in Research/Science  18 upvotes 4 years ago
      A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

      community Finasteride and Its Effects on Cognition: Where's the Science?

      in Research/Science  26 upvotes 4 years ago
      The user shared their experience with hair loss treatments, including low-dose minoxidil, finasteride, and essential oils, and expressed concerns about the cognitive side effects of finasteride. They are seeking more information on how finasteride may affect cognition and are considering whether to continue or stop the treatment.

      community Reaction to High Dose Minoxidil After Year of Use

      in Minoxidil  11 upvotes 5 years ago
      A male with early-stage hair loss experienced severe side effects, including sexual dysfunction from finasteride and increased heart rate and fatigue from high-dose minoxidil, leading to discontinuation of both treatments. He is now relying on DHT-blocking shampoos and awaiting new treatments.

      community Pumpkin seed oil actually helps with hair loss (MPB) see study

       54 upvotes 5 years ago
      Pumpkin seed oil is discussed as a potential treatment for hair loss, but the study cited is criticized for using a product with multiple ingredients, making it unclear if pumpkin seed oil is effective. The conversation concludes with skepticism about the study's validity and mentions that pumpkin seeds might help with DHT blocking.

      community Vitamin E

       20 upvotes 6 years ago
      Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.

      community I have a theory that scalp massage works.

       17 upvotes 6 years ago
      Scalp massage may help with hair growth by stimulating blood flow, similar to minoxidil. Users discuss its potential benefits and share personal experiences, noting it might reduce DHT levels and improve hair health.

      community 5 month update on my all natural protocol

      in Update  7 upvotes 6 years ago
      The user updated on their all-natural hair loss protocol, which includes massages, LLLT, Ashwagandha, Supergreens mix, Vitamin D, Castor Oil + DMSO, a specific diet, and headstands. They reported some hair regrowth and improved hair quality, with plans to continue the regimen and monitor results.

      community Had sides on finasteride ? A word of hope.

      in Finasteride  26 upvotes 6 years ago
      A user's experience with hair loss treatments, including finasteride and other options such as RU58841, Nizoral, Pumpkin Seed, and Adenosine; the importance of being in a positive frame of mind when considering taking finasteride; and the need to address life issues before starting finasteride.

      community Methionine? Glycine?

       6 upvotes 8 years ago
      The conversation discusses the potential benefits and risks of using Methionine and Glycine for hair loss, with concerns about cancer risk if not balanced properly. The user seeks opinions on these amino acids for hair health and overall benefits.

      community im 23, hair loss problem

       7 upvotes 9 years ago
      A 23-year-old experiencing hair loss tried olive oil, coconut oil, and hair growth shampoos without success. They are seeking advice on whether to start treatments like Minoxidil, finasteride, or RU58841.

      community Wtf have we been doing for the last 30 years

      in Treatment  540 upvotes 1 week ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

      community Do hair follicles dies or are dormant ?

      in Finasteride/Dutasteride  92 upvotes 1 month ago
      Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

      community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

      in Finasteride/Dutasteride  49 upvotes 1 month ago
      Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

      community Results after 6 months of treatment

      in Progress Pictures  1802 upvotes 1 month ago
      Significant hair regrowth was achieved after six months using finasteride and minoxidil, with no side effects reported. The user plans to taper off minoxidil and is considering oral minoxidil, but is cautious due to potential heart issues.

      community Why isnt topical fin talked about more?

      in Chat  44 upvotes 1 month ago
      Topical finasteride is less popular due to inconvenience, cost, and availability, while oral finasteride is favored for ease and safety. Some users experience side effects with topical use, but find it effective with minoxidil, though opinions on its efficacy vary.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 month ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Bryan Johnson used a customized formula by Roots byGA to restore his hair

      in Treatment  23 upvotes 1 month ago
      Bryan Johnson used a customized hair restoration formula from Roots byGA, which includes Minoxidil, Cetirizine HCl, Latanoprost, Dutasteride, Melatonin, Caffeine, Tretinoin, Vitamin D3, and Vitamin E. Many users are skeptical of the effectiveness and uniqueness of the treatment, suggesting that standard treatments like Minoxidil and Dutasteride are more reliable.

      community How are people getting DUT so easily?

      in Finasteride/Dutasteride  15 upvotes 1 month ago
      Dutasteride is hard to get in Europe due to prescription rules, leading some to consider online pharmacies or travel. Users discuss alternatives like private doctors and compare it to finasteride, expressing concerns about side effects and effectiveness.