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Glossarypropylene glycol

synthetic liquid that enhances skin absorption of active ingredients

Propylene glycol is a synthetic liquid substance that absorbs water and is commonly used as a solvent in pharmaceuticals, including topical treatments for hair and skin conditions. It helps active ingredients penetrate the skin more effectively and is generally considered safe for use, though some individuals may experience skin irritation.

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community How are you managing sex life when applying to topical minoxidil?

in Minoxidil 99 upvotes 1 year ago

User asks how to manage sex life while using topical minoxidil for hair loss. Responses suggest various strategies, including using finasteride, applying minoxidil before or after sex, and avoiding certain positions.

community Propylene glycol vs ethyl alcohol(70% or 96%) for topical finasteride solution. Pros and cons?

in Finasteride/Dutasteride 4 upvotes 8 months ago

The conversation discusses the pros and cons of using propylene glycol versus ethyl alcohol in topical solutions for finasteride and minoxidil. It questions why propylene glycol is commonly used and whether ethyl alcohol might be a better option.

community Topical Finasteride -- Without Propylene Glycol (PG)

in Finasteride/Dutasteride 2 upvotes 3 years ago

The user seeks alternatives to Propylene Glycol (PG) for delivering topical finasteride due to scalp irritation. They consider using Propanediol 1,3 and ask for other suggestions.

community Can use olive oil instead of PG (propylene glycol) or glycerin in topical finasteride preparation?

in Finasteride/Dutasteride 2 upvotes 4 months ago

A user asked if olive oil can replace propylene glycol or glycerin in topical finasteride preparation. Another user advised against it, suggesting MCT oil instead due to olive oil's potential to worsen dandruff and seborrheic dermatitis.

community Irritation from topical min (maybe propylene glycol)

in Minoxidil 7 upvotes 2 years ago

User experienced scalp irritation from Kirkland 5% liquid minoxidil, likely due to propylene glycol. They are seeking non-PG liquid alternatives that are affordable.

community Where can I buy RU58841 from? Really need it without propylene glycol as well. Anyone else tried RU ? thanks

6 upvotes 9 years ago

The conversation is about where to buy RU58841 without propylene glycol. The user also asks if anyone else has tried RU58841.

community Anyone in Australia found topical versions of minoxidil and finasteride that are free of Propylene Glycol?

in Treatment 1 upvotes 5 months ago

A user is seeking topical versions of minoxidil and finasteride in Australia that do not contain propylene glycol. They are looking for alternatives due to potential irritation from propylene glycol.

community 29M, 5.5 months of: 0.5mg finasteride, 5% minoxidil, 1.5mm microneedling once a week and 20mg RU58841. No notable sides. I feel much better, and happy to have started treatment just in time. I just wish I started sooner! The dandruffy gunk you see is definitely propylene glycol from minoxidil :')

in Progress Pictures 565 upvotes 3 years ago

User shared 5.5-month progress using 0.5mg finasteride, 5% minoxidil, 1.5mm microneedling weekly, and 20mg RU58841, with positive results and no side effects. Others discussed their experiences, dosage adjustments, and the importance of age in treatment efficacy.

community My personal experience/observations fighting AGA seriously for 5 years

in Treatment 43 upvotes 2 weeks ago

Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.

community Diy topical fin chunks on bottom

in Finasteride/Dutasteride 5 upvotes 5 months ago

A user made a 70/30 ethanol/propylene glycol topical finasteride solution but noticed chunks at the bottom. The discussion focuses on this issue with the DIY hair loss treatment.

community What do you mix your RU58841 powder with?

in Product 1 upvotes 2 months ago

RU58841 powder is mixed with a 70% ethanol and 30% propylene glycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.

community Does anyone homebrew their own minox/ru58841

in Chat 1 upvotes 7 months ago

A bodybuilder discusses homebrewing Minoxidil and RU58841 using propylene glycol or MCT. They inquire about the feasibility and potential risks of these methods.

community Question about RU58841 in minoxidil

in Minoxidil 5 upvotes 3 years ago

The user is considering adding RU58841 to liquid minoxidil without propylene glycol (PG) due to an allergy and is asking if this combination is effective and if PG is necessary. They have been using finasteride and minoxidil foam, plan to use RU58841 with liquid minoxidil in the evening, and continue finasteride.

community Hims topical min/fin spray vs serum

in Treatment 9 upvotes 8 months ago

The conversation is about someone switching from a hair loss treatment spray with alcohol and propylene glycol to a serum with essential oils, questioning the absorption and effectiveness of the new product. The spray and serum both contain 0.3% finasteride and 6% minoxidil.

community Question about making a solution of RU58841

in Treatment 1 upvotes 1 year ago

The conversation is about making a solution of RU58841 using propanediol instead of propylene glycol due to skin irritation. The user seeks advice on whether this substitution is acceptable.

community Can I use wound cleanser to make topical finasteride, it contains 70% IPA and rest Purified Water?

in Finasteride/Dutasteride 4 upvotes 6 months ago

The user wants to make a topical finasteride solution using wound cleanser with 70% IPA and add 40% propylene glycol due to headaches from minoxidil. They seek advice on using the wound cleanser and recommendations for pharmaceutical/cosmetic grade IPA in India.

community How to mix ru-powder with European ingredients?

in Product 1 upvotes 7 months ago

A user seeks advice on mixing RU58841 serum using European ingredients, specifically struggling to find propylene glycol. They are looking for alternatives to American products commonly recommended in guides.

community Anyone have an alternative solvent for pyrilutamide??

in Product 2 upvotes 1 year ago

The user is seeking an alternative solvent for pyrilutamide due to skin irritation from ethanol and propylene glycol. They experienced similar issues with topical minoxidil.

community Creating Your Own Topicals: A Guide

in Research/Science 67 upvotes 1 year ago

Creating a carrier solution for topical hair loss treatments using ethanol, propylene glycol or glycerin, and instructions on creating topical finasteride. Different recipes are provided with varying ratios of alcohol to humectant.

community Can I mix finasteride in just water for topical?

in Finasteride/Dutasteride 5 upvotes 2 years ago

The conversation is about whether finasteride can be mixed with just water for a topical solution and if Isopropyl Alcohol and Propylene Glycol are necessary for effectiveness and faster drying. The user is seeking advice on the formulation of topical finasteride.

community Failure with 5mg oral minoxidil, looking for experiences of people who used topical with glycerin as a vehicle.

in Minoxidil 6 upvotes 2 months ago

Oral minoxidil was ineffective for OP, causing hair loss and unwanted body hair, while topical minoxidil showed significant regrowth. OP is switching to topical minoxidil with glycerin due to scalp issues with propylene glycol.

community Kintors interim report from 9-2-24 for everyone whos interested

in Product 34 upvotes 3 months ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community Should topicals be massaged thoroughly into the scalp ?

in Minoxidil 3 upvotes 5 months ago

Topicals like minoxidil and finasteride should reach the scalp, but excessive massaging can cause hair to fall out. The evaporation felt is likely the carrier substances like alcohol or propylene glycol.

community AttentionHomemade Topical Fin Users- requesting Feedback

in Finasteride/Dutasteride 4 upvotes 5 months ago

A user is seeking feedback on a homemade topical finasteride formula for hair loss, consisting of 7.5 mg of finasteride, propylene glycol, ethanol, and distilled water. They aim to achieve a 0.0125% solution by applying 2 ml daily.

community Solvent for topical fin with low absorption

in Product 2 upvotes 5 months ago

The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

community Homemade finasteride foam similar to minoxidil foam

in Product 5 months ago

A user is seeking advice on creating a homemade finasteride foam similar to over-the-counter Minoxidil foam, due to issues with glycerin and propylene glycol in their current solutions. They are considering using a mixture of ethanol/alcohol and water for the foam.

community Any UK sources for minoxidil+RU58841 solution together? That doesn’t contain PG?

in Treatment 2 upvotes 6 months ago

A user is seeking a UK source for a combined minoxidil and RU58841 solution that doesn't contain scalp-irritating ingredients. They specifically want a product without propylene glycol (PG).

community Anyone using Finastopic (no pg Isdin)?

in Product 2 upvotes 7 months ago

The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.

community Effects of 2% vs 5% min for sebderm

in Minoxidil 1 upvotes 7 months ago

Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

community The best vehicle/carrier for RU58841

in Treatment 2 upvotes 1 year ago

The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.